PMID

Data

Article Title

Organization

Sodium Channel Blockers.

Temple University

Bicyclic Ketone Sulfonamide Compounds.

Temple University

Design, synthesis, and evaluation of (2S,4R)-Ketoconazole sulfonamide analogs as potential treatments for Metabolic Syndrome.

Temple University

N-(2-Alkyleneimino-3-phenylpropyl)acetamide Compounds and Their Use against Pain and Pruritus via Inhibition of TRPA1 Channels.

Temple University

PPAR Agonists, Compounds, Pharmaceutical Compositions, and Methods of Use Thereof.

Temple University

PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas.

Temple University

Inhibitors of Renal Outer Medullary Potassium Channel.

Temple University

Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Temple University

Sulfonamide Compounds as Voltage Gated Sodium Channel Modulators.

Temple University

Sulfonamide Derivatives and Pharmaceutical Applications Thereof.

Temple University

Cyclopropanamine Compounds and Use Thereof.

Temple University

Fused Morphlinopyrimidines and Methods of Use Thereof.

Temple University

Inhibitors of the Renal Outer Medullary Potassium Channel.

Temple University

Novel Pyrazine Amide Compounds.

Temple University

Pyrrolopyridine or Pyrazolopyridine Derivatives.

Temple University

4,6-Diarylaminothiazines as BACE1 Inhibitors and Their Use for the Reduction of Beta-Amyloid Production.

Temple University

Biphenyl-ethyl-pyrrolidine derivatives as histamine h3 receptor modulators for the treatment of cognitive disorders.

Temple University

Imidazo[2,1]thiazol-3-one Derivatives Useful as Diagnostic Agents for Alzheimer's Disease.

Temple University

Fused Thiazin-3-ones as KCa3.1 Inhibitors.

Temple University

N-[4-(1H-Pyrazolo[3,4-B]pyrazin-6yl)-phenyl]-sulonamides and Their Use As Pharmaceuticals.

Temple University

Cyclopropyl-Fused 1,3-Thiazepines as BACE1 and BACE2 Inhibitors.

Temple University

Selective Cyp11B1 Inhibitors for the Treatment of Cortisol Dependent Diseases.

Temple University

Aldosterone synthase inhibitors.

Temple University

Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.

Temple University

Design, synthesis and evaluation of (E)-alpha-benzylthio chalcones as novel inhibitors of BCR-ABL kinase.

Temple University

Identification of a chromone-based retinoid containing a polyolefinic side chain via facile synthetic routes.

Temple University

Cyclic ADP Ribose Hydrolase (CD38) Inhibitors.

Temple University

Discovery and SAR of Novel Disubstituted Quinazolines as Dual PI3Kalpha/mTOR Inhibitors Targeting Breast Cancer.

Temple University

The Resurrection of Phenotypic Drug Discovery.

Temple University

Pyrrolo-pyridazine Derivatives as Muscarinic M

Temple University

Carboxamides as Modulators of Sodium Channels.

Temple University

Novel Potassium Channel Inhibitors.

Temple University

2-Amino-N-heteroaryl-nicotimamides as Na

Temple University

Novel compounds that reverse the disease phenotype in Type 2 Gaucher disease patient-derived cells.

Temple University

Sodium Channel Modulators and Their Method of Use.

Temple University

Tricyclic Inhibitors of β-Secretase and Their Methods of Use for the Treatment of Alzheimer's Disease.

Temple University

Bridged Piperidine Derivatives Useful as γ-Secretase Inhibitors for the Treatment of Alzheimer's Disease.

Temple University

Triazolo Pyridines Useful as Inhibitors of γ-Secretase and Their Methods of Use.

Temple University

Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D

Temple University

Modulators of KEAP-1 Activity as Potential Therapies for the Treatment of Neurodegenerative Disorders.

Temple University

Triazolo-azepine Inhibitors of γ-Secretase and Their Methods of Use.

Temple University

5-Aryl-1-imino-1-oxo-[1,2,4]thiadiazines.

Temple University

Orally active opioid compounds from a non-poppy source.

Temple University

Azabicyclic Fused Pyrimidine Derivatives Useful for the Treatment of Alzheimer's Disease.

Temple University

Azabicyclic Fused Pyrimidine Derivatives Useful for the Treatment of Alzheimer's Disease.

Temple University

Allosteric Modulators of Nicotinic Acetylcholine Receptors Useful for the Treatment of Cognitive Impairment.

Temple University

Acyl Sulfonamides NaV1.7 Blockers Useful for the Treatment of Pain.

Temple University

Covalent Inhibitors of the TEC Family of Kinases and Their Methods of Use.

Temple University

Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin.

Temple University

Interrogating the Roles of Post-Translational Modifications of Non-Histone Proteins.

Temple University

Design and synthesis of functionalized piperazin-1yl-(E)-stilbenes as inhibitors of 17α-hydroxylase-C17,20-lyase (Cyp17).

Temple University

C

Temple University

Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase-A and -B.

Temple University

Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.

Temple University

A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF

Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

9H-pyrrolo-dipyridine derivatives

Ucb Biopharma

Pyridinamine-pyridone and pyrimidinamine- pyridone compounds

Sprint Bioscience

Selective NR2B antagonists

Bristol-Myers Squibb

Fused amino pyridine as HSP90 inhibitors

Curis

2′-chloro nucleoside analogs for HCV infection

Idenix Pharmaceuticals

 

Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles

Hacettepe University

Aryl sulfamide and sulfamate derivatives as RORc modulators

Genentech

Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor.

Duke University