Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50006721
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502723(CHEMBL4462699 | US11479539, Compound 196)
Affinity DataEC50:  18nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502724(CHEMBL4463989 | US11479539, Compound 122)
Affinity DataEC50:  24nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502725(CHEMBL4565642 | US11479539, Compound 168)
Affinity DataEC50:  7nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502726(CHEMBL4583328 | US11479539, Compound 55)
Affinity DataEC50:  14nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502727(CHEMBL4584154 | US11479539, Compound 48)
Affinity DataEC50:  6nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502728(CHEMBL4542755 | US11479539, Compound 174)
Affinity DataEC50:  8nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502729(CHEMBL4593124 | US11479539, Compound 23)
Affinity DataEC50:  56nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502730(CHEMBL4535670)
Affinity DataEC50:  45nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502731(CHEMBL4530659)
Affinity DataEC50:  70nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502732(CHEMBL4557371 | US11479539, Compound 69)
Affinity DataEC50:  2nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502733(CHEMBL4446699 | US11479539, Compound 80)
Affinity DataEC50:  2nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50502734(CHEMBL4442320 | US11479539, Compound 42)
Affinity DataEC50:  33nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed