Target Names are taken from UniProtKB. To view the associated UniProt page, click on the UniProt ID. When we have data for a given Target in multiple species or for mutants of a given Target, we provide a header row (upper case, bold font) with all of the data followed by a separate for each species or variant of the Target.
Target Name
Organism
Affinity Links
Articles
UniProts
Files
Human
Human
Human
Human
Human
Human
Human
Dual specificity mitogen-activated protein kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase P04049 Q02750
Human
IC50: 26
Human
IC50: 18
Human
IC50: 18
KRAS (G12D)/Son of Sevenless Homolog 1 (SOS)/RAF Proto-Oncogene Serine/Threonine-Protein Kinase (c-Raf) P04049 Q07889
Human
IC50: 21
Mitogen-activated protein kinase kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase P04049 Q13233
Human
Kd: 38
Human
Human
IC50: 96
IC50: 16
Human
IC50: 62
Human
IC50: 127
Human
IC50: 1923
Human
IC50: 2
Human
Human
Ki: 1
Human
Ki: 1
RECEPTOR PROTEIN-TYROSINE KINASE A0A8C0LZB8 A0A8I3MXT5 O00329 P21980 P42336 P42345 P78527 Q2XPT7 Q504U8
IC50: 22
Human
IC50: 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Receptor protein-tyrosine kinase P42336 Q504U8
Human
IC50: 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/Receptor protein-tyrosine kinase O00329 Q504U8
Human
IC50: 1
Human
IC50: 1
Human
Human
Human
Human
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 P53779 Q13546
Human
EC50: 25
Human
Mouse
Human
Human
Human
Severe acute respiratory syndrome coronavirus (SARS-CoV)
REPLICASE POLYPROTEIN 1AB A0A3G5BIY8 K9N7C7 P0C6W3 P0C6W4 P0C6W5 P0C6X1 P0C6X4 P0C6X5 P0C6X6 P0C6X7 P0C6X9 P0C6Y2 P0C6Y4 P0DTD1 Q98VG9
Human SARS coronavirus (SARS-CoV)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
IC50: 15
Human
Human
Ki: 1
RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA O43924 P04972 P11541 P16499 P16586 P18545 P22571 P23439 P35913 P51160 Q13956 Q95142
Human
RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA O43924 P04972 P11541 P16499 P16586 P18545 P22571 P23439 P35913 P51160 Q13956 Q95142
Human
Bovine
IC50: 68
RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA O43924 P04972 P11541 P16499 P16586 P18545 P22571 P23439 P35913 P51160 P54827 Q13956 Q95142
Human
Bovine
IC50: 68
RETINOIC ACID RECEPTOR RXR-ALPHA P10276 P10827 P10828 P11473 P19793 P28700 P28702 P37231 P48443 P55055 Q05343 Q13133
Human
Human
Human
EC50: 36
Human
EC50: 22
Human
Human
EC50: 27
Human
EC50: 27
Human
Human
Human immunodeficiency virus type 1
Human immunodeficiency virus type 1
Human immunodeficiency virus type 1
Human
IC50: 11
Human
IC50: 10
Human
Human
Human
Human
IC50: 1
Human
Human
Human
Human
Human
Human
Human
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Kd: 4
Hepatitis C virus genotype 1b (isolate Con1) (HCV)
Polymerase acidic protein/Polymerase basic protein 2/RNA-directed RNA polymerase catalytic subunit P03428 P03431 P03433
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
EC50: 1
Human respiratory syncytial virus A (strain A2)
EC50: 87
ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA O43924 P04972 P11541 P16499 P16586 P18545 P22571 P23439 P35913 P51160 Q13956 Q28263 Q95142
Human
Bovine
IC50: 68
ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA O43924 P04972 P11541 P16499 P16586 P18545 P22571 P23439 P35913 P51160 Q13956 Q95142
Human
Bovine
IC50: 68
Staphylococcus aureus subsp. aureus N315
Human
EC50: 13

