BDB TargetNames

Target Names are taken from UniProtKB. To view the associated UniProt page, click on the UniProt ID. When we have data for a given Target in multiple species or for mutants of a given Target, we provide a header row (upper case, bold font) with all of the data followed by a separate for each species or variant of the Target.

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Target Name

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1,25-DIHYDROXYVITAMIN D(3) 24-HYDROXYLASE, MITOCHONDRIAL Q07973 Q09128

Ki: 39 IC50: 121 EC50: 3

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial Q07973

Human

Ki: 39 IC50: 101 EC50: 3

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial Q09128

Rat

IC50: 20

1,3-beta-D-glucan synthase catalytic subunit O13383

Yeast

IC50: 151

1,3-BETA-GLUCAN SYNTHASE B6S6L8 E2GKZ4 F5BCZ9 O13423 O13428 P87204 Q4U2W2 Q4WLT4

IC50: 207 EC50: 8

1,3-beta-glucan synthase O13428

Yeast

IC50: 72

1,3-beta-glucan synthase Q4WLT4

Neosartorya fumigata (Aspergillus fumigatus)

IC50: 7

1,3-beta-glucan synthase F5BCZ9

Yeast

IC50: 53 EC50: 8

1,3-beta-glucan synthase O13423

Yeast

IC50: 43

1,3-beta-glucan synthase Q4U2W2

Yeast

IC50: 2

1,3-beta-glucan synthase P87204

Neosartorya fumigata

IC50: 3

1,3-beta-glucan synthase B6S6L8

Yeast

IC50: 15

1,3-beta-glucan synthase E2GKZ4

Yeast

IC50: 12

1,3-beta-glucan synthase component GSC2 P40989

Baker's yeast

Ki: 1 IC50: 57 EC50: 2

1,4-dihydroxy-2-naphthoate octaprenyltransferase P9WIP3

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 32

1,4-dihydroxy-2-naphthoyl-CoA synthase P9WNP5

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 12 IC50: 37

1,5-anhydro-D-fructose reductase Q96JD6

Human

IC50: 70

1-acyl-sn-glycerol-3-phosphate acyltransferase beta O15120

Human

IC50: 135

1-alkyl-2-acetylglycerophosphocholine esterase Q6UB75

Pig

IC50: 3

1-aminocyclopropane-1-carboxylate oxidase 1 Q00985

Apple

Ki: 4

1-aminocyclopropane-1-carboxylate synthase 5 Q37001

Mouse-ear cress

Ki: 2 IC50: 4

1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE A0QVH7 P45568 P9WNS1 Q55663

Ki: 56 IC50: 238 Kd: 10

1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568

Escherichia coli (strain K12)

Ki: 34 IC50: 139

1-deoxy-D-xylulose 5-phosphate reductoisomerase Q55663

Synechocystis sp. (strain PCC 6803 / Kazusa)

Ki: 6

1-deoxy-D-xylulose 5-phosphate reductoisomerase P9WNS1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 16 IC50: 94 Kd: 10

1-deoxy-D-xylulose 5-phosphate reductoisomerase A0QVH7

Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacteriumsmegmatis)

IC50: 5

1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic Q8IKG4

Plasmodium falciparum (isolate 3D7)

Ki: 1 IC50: 25

1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic Q9XFS9

Mouse-ear cress

IC50: 3

1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE B7UJP3 P77488 P9WNS3 Q4QKG6 Q9RUB5

Ki: 12 IC50: 41 Kd: 2

1-deoxy-D-xylulose-5-phosphate synthase P77488

Escherichia coli (strain K12)

Ki: 7 IC50: 8

1-deoxy-D-xylulose-5-phosphate synthase P9WNS3

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 1 IC50: 29 Kd: 1

1-deoxy-D-xylulose-5-phosphate synthase B7UJP3

Escherichia coli O127:H6 (strain E2348/69 / EPEC)

Ki: 3

1-deoxy-D-xylulose-5-phosphate synthase Q4QKG6

Haemophilus influenzae (G-proteobacteria)

Ki: 1 IC50: 2

1-deoxy-D-xylulose-5-phosphate synthase Q9RUB5

Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 /LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

IC50: 2 Kd: 1

1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic Q38854

Mouse-ear cress

IC50: 5

1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE Q9Y2I7

Human

IC50: 183 Kd: 70

1-phosphatidylinositol 3-phosphate 5-kinase Q9Y2I7

Human

IC50: 154 Kd: 70

1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] Q9Y2I7

Human

IC50: 29

1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1 P10687 Q9NQ66

Ki: 2 IC50: 1 EC50: 3

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 P10687

Rat

Ki: 2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 Q9NQ66

Human

IC50: 1 EC50: 3

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Q01970

Human

IC50: 157

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 Q62711

Rat

Ki: 1

1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1 P08487 P10686 P19174

IC50: 273 EC50: 1 ITC: 7

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 P19174

Human

IC50: 97 EC50: 1

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 P08487

Bovine

IC50: 17

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 P10686

Rat

IC50: 2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T] P19174

Human

IC50: 157

Phospholipase C-γ1 SH2 domain (PLCC) P19174

Human

ITC: 7

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 P16885

Human

IC50: 15

Phosphatidylinositol 4-kinase Q5CVD3

Cryptosporidium parvum (strain Iowa II)

IC50: 29

1-phosphatidylinositol phosphodiesterase P14262

Bacillus cereus

Ki: 3 IC50: 6 Kd: 3

11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 P16232 P28845 P50172 Q56D22 Q5XX84

Ki: 448 IC50: 5863 Kd: 1 EC50: 100 Other: 10

11-beta-hydroxysteroid dehydrogenase 1 P28845

Human

Ki: 326 IC50: 4520 Kd: 1 EC50: 37 Other: 10

11-beta-hydroxysteroid dehydrogenase 1 P50172

Mouse

Ki: 87 IC50: 1154 EC50: 18

11-beta-hydroxysteroid dehydrogenase 1 P16232

Rat

Ki: 34 IC50: 109

11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] P28845

Human

IC50: 31

11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S] P28845

Human

IC50: 46 EC50: 45

Hydroxysteroid 11-beta dehydrogenase 1 Q56D22

Rhesus macaque

IC50: 1

Hydroxysteroid 11-beta dehydrogenase 1 Q5XX84

Dog

Ki: 1 IC50: 2

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 P50233 P51661 P80365

Ki: 3 IC50: 980 EC50: 8

11-beta-hydroxysteroid dehydrogenase type 2 P80365

Human

Ki: 3 IC50: 643 EC50: 4

11-beta-hydroxysteroid dehydrogenase type 2 P51661

Mouse

IC50: 301 EC50: 4

11-beta-hydroxysteroid dehydrogenase type 2 P50233

Rat

IC50: 36

14 kDa phosphohistidine phosphatase Q9NRX4

Human

Ki: 3 IC50: 5

14-3-3 protein beta/alpha P31946

Human

Kd: 1

14-3-3 protein eta Q04917

Human

Kd: 13

14-3-3 protein gamma P61981

Human

IC50: 57

14-3-3 protein sigma P31947

Human

IC50: 6 Kd: 1

14-3-3 protein theta P27348

Human

Kd: 1

14-3-3 protein zeta/delta P63104

Human

IC50: 6 Kd: 25 EC50: 1

Lanosterol 14a-demethylase Q96W81

Neosartorya fumigata

Kd: 6

15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] O08699 P15428 Q8VCC1

Ki: 3 IC50: 976

15-hydroxyprostaglandin dehydrogenase [NAD(+)] O08699

Rat

IC50: 1

15-hydroxyprostaglandin dehydrogenase [NAD(+)] Q8VCC1

Mouse

IC50: 1

15-hydroxyprostaglandin dehydrogenase [NAD(+)] P15428

Human

Ki: 3 IC50: 974

17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 Q7Z5P4 Q8VCR2

Ki: 17 IC50: 1430

17-beta-hydroxysteroid dehydrogenase 13 Q7Z5P4

Human

Ki: 11 IC50: 1404

17-beta-hydroxysteroid dehydrogenase 13 Q8VCR2

Mus musculus

Ki: 6 IC50: 26

17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1

Human

Ki: 49

17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 P14061 P51656

Ki: 13 IC50: 865 Other: 14

17-beta-hydroxysteroid dehydrogenase type 1 P14061

Human

Ki: 13 IC50: 861 Other: 14

17-beta-hydroxysteroid dehydrogenase type 1 P51656

Mouse

IC50: 4

17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 P37059 P51659

Human

Ki: 1 IC50: 816

Peroxisomal multifunctional enzyme type 2 P51659

Human

IC50: 15

Peroxisomal multifunctional enzyme type 2 P37059

Human

Ki: 1 IC50: 801

17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 O54939 P37058 P70385

IC50: 305

17-beta-hydroxysteroid dehydrogenase type 3 P37058

Human

IC50: 281

17-beta-hydroxysteroid dehydrogenase type 3 O54939

Rat

IC50: 23

17-beta-hydroxysteroid dehydrogenase type 3 P70385

Mouse

IC50: 1

17beta-hydroxysteroid dehydrogenase O93874

Filamentous fungus

IC50: 18

1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase P9WJN3

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 3 IC50: 6

2''-aminoglycoside nucleotidyltransferase P0AE05

Pseudomonas aeruginosa (g-Proteobacteria)

Ki: 2

2',5'-phosphodiesterase 12 Q6L8Q7

Human

Ki: 1 IC50: 2

2'-phosphotransferase Q5A7N4

Yeast

IC50: 19

Siderophore-binding protein A0A045J7I4

Mycobacterium tuberculosis

Ki: 22

2,6-dichloro-p-hydroquinone 1,2-dioxygenase Q9ZBB0

Sphingobium chlorophenolicum

Ki: 4

2-5A-DEPENDENT RIBONUCLEASE Q05823 Q05921

IC50: 56 Kd: 4 EC50: 71

2-5A-dependent ribonuclease Q05823

Human

IC50: 27 Kd: 4 EC50: 65

2-5A-dependent ribonuclease Q05921

Mouse

IC50: 29 EC50: 6

2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 Q3SYC2 Q80W94

IC50: 278

2-acylglycerol O-acyltransferase 2 Q3SYC2

Human

IC50: 246

2-acylglycerol O-acyltransferase 2 Q80W94

Mouse

IC50: 32

2-acylglycerol O-acyltransferase 3 Q86VF5

Human

IC50: 1

2-amino-3-carboxymuconate-6-semialdehyde decarboxylase Q8TDX5

Human

Ki: 2 IC50: 155

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase X5EH84

Staphylococcus aureus

IC50: 2 Kd: 73

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase P26281

Escherichia coli (strain K12)

IC50: 15 Kd: 66

Quinolone signal response protein A0A072ZMX8

Pseudomonas aeruginosa

Kd: 2

2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE P62617 Q63T71 Q8ZMF7

IC50: 5 Kd: 20 Other: 3

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase P62617

Escherichia coli (strain K12)

IC50: 3 Kd: 7 Other: 3

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q8ZMF7

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

IC50: 2

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q63T71

Burkholderia pseudomallei (strain K96243)

Kd: 13

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic Q9CAK8

Mouse-ear cress

IC50: 1

2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Q8FEJ5

Escherichia coli O6

Ki: 1

2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic P69834

Mouse-ear cress

IC50: 4

2-dehydro-3-deoxyphosphooctonate aldolase Q9JZ55

Neisseria meningitidis serogroup B (strain MC58)

Ki: 6

2-dehydropantoate 2-reductase P0A9J4

Escherichia coli (strain K12)

Ki: 6 Kd: 12

2-HYDROXYACID OXIDASE 1 B0BNF9 Q9UJM8 Q9WU19

Ki: 11 IC50: 568 EC50: 10

2-Hydroxyacid oxidase 1 Q9UJM8

Human

Ki: 6 IC50: 531 EC50: 1

2-Hydroxyacid oxidase 1 B0BNF9

Rat

IC50: 1

2-Hydroxyacid oxidase 1 Q9WU19

Mouse

Ki: 5 IC50: 36 EC50: 9

2-HYDROXYACID OXIDASE 2 Q07523 Q9NYQ3

IC50: 45

2-Hydroxyacid oxidase 2 Q07523

Rat

IC50: 44

2-Hydroxyacid oxidase 2 Q9NYQ3

Human

IC50: 1

2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE Q16880 Q64676

IC50: 40

2-hydroxyacylsphingosine 1-beta-galactosyltransferase Q16880

Human

IC50: 38

2-hydroxyacylsphingosine 1-beta-galactosyltransferase Q64676

Mouse

IC50: 2

Putative glyoxylate/hydroxypyruvate reductase B Q9X4A4

Staphylococcus aureus

IC50: 63

2-OXOGLUTARATE RECEPTOR 1 Q6Y1R5 Q96P68

Ki: 40 IC50: 8

2-oxoglutarate receptor 1 Q6Y1R5

Rat

Ki: 40

2-oxoglutarate receptor 1 Q96P68

Human

IC50: 8

23S rRNA methylase leader peptide P10739

Escherichia coli

IC50: 2

25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL O15528 O35084

Ki: 26 IC50: 27

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial O15528

Human

Ki: 7 IC50: 10

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial O35084

Mouse

Ki: 19 IC50: 17

26S proteasome non-ATPase regulatory subunit 10 O75832

Human

Kd: 2

26S proteasome non-ATPase regulatory subunit 11 O00231

Human

Kd: 2

26S proteasome non-ATPase regulatory subunit 14 O00487

Human

IC50: 516

26S proteasome regulatory subunit 6B P43686

Human

IC50: 2

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase P9WQP7

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 20

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 P14060

Human

Ki: 13 IC50: 2

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 P26439

Human

IC50: 4

3',5'-cyclic-AMP phosphodiesterase O77823

Pig

IC50: 87 EC50: 1

3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4A O89084 O89085 P14270 P14644 P14646 P27815 P54748 Q01063 Q07343 Q08493 Q08499 Q3UEI1 Q8VBU5

Ki: 350 IC50: 2820 Kd: 2 EC50: 30

Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) P27815

Human

IC50: 91

Isoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (PDE4A8) P27815

Human

IC50: 58

Phosphodiesterase/cAMP-specific 3',5'-cyclic phosphodiesterase 4A/cAMP-specific 3',5'-cyclic phosphodiesterase 4C/cAMP-specific 3',5'-cyclic phosphodiesterase 4D O89084 Q01063 Q3UEI1 Q8VBU5

Mouse

IC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A P27815

Human

Ki: 104 IC50: 995 EC50: 16

cAMP-specific 3',5'-cyclic phosphodiesterase 4A O89085

Guinea pig

Ki: 1

cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] P27815

Human

IC50: 135

cAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660] P27815

Human

IC50: 5

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P27815 Q07343 Q08493 Q08499

Human

Ki: 239 IC50: 1488 Kd: 2 EC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P14270 P14644 P14646 P54748

Rat

Ki: 6 IC50: 34

3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4B P14270 P14644 P14646 P27815 P54748 Q07343 Q08493 Q08499

Ki: 469 IC50: 5511 Kd: 2 EC50: 16

Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B Q07343

Human

IC50: 374

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P27815 Q07343 Q08493 Q08499

Human

Ki: 239 IC50: 1488 Kd: 2 EC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P14270 P14644 P14646 P54748

Rat

Ki: 6 IC50: 34

cAMP-specific 3',5'-cyclic phosphodiesterase 4B Q07343

Human

Ki: 198 IC50: 2967 EC50: 2

cAMP-specific 3',5'-cyclic phosphodiesterase 4B P14646

Rat

Ki: 26 IC50: 42

cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] Q07343

Human

IC50: 104

cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] Q07343

Human

IC50: 162

cAMP-specific 3',5'-cyclic phosphodiesterase 4B [316-320,321-700,S319G,N320S,N321H,T322M] Q07343

Human

IC50: 31

cAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D] Q07343

Human

IC50: 309

3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4C O89084 P14270 P14644 P14646 P27815 P54748 Q01063 Q07343 Q08493 Q08499 Q3UEI1 Q8VBU5

Ki: 264 IC50: 2314 Kd: 2 EC50: 14

Phosphodiesterase/cAMP-specific 3',5'-cyclic phosphodiesterase 4A/cAMP-specific 3',5'-cyclic phosphodiesterase 4C/cAMP-specific 3',5'-cyclic phosphodiesterase 4D O89084 Q01063 Q3UEI1 Q8VBU5

Mouse

IC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P27815 Q07343 Q08493 Q08499

Human

Ki: 239 IC50: 1488 Kd: 2 EC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P14270 P14644 P14646 P54748

Rat

Ki: 6 IC50: 34

cAMP-specific 3',5'-cyclic phosphodiesterase 4C Q08493

Human

IC50: 389

cAMP-specific 3',5'-cyclic phosphodiesterase 4C P14644

Rat

Ki: 19 IC50: 255

cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712] Q08493

IC50: 134

3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4D O89084 P14270 P14644 P14646 P27815 P54748 Q01063 Q07343 Q08493 Q08499 Q3UEI1 Q8VBU5

Ki: 400 IC50: 5217 Kd: 11 EC50: 23

Isoform 10 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (10) Q08499

Human

IC50: 13

Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) Q08499

Human

IC50: 255

Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) 0-562] Q08499

Human

IC50: 65

Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672] Q08499

Human

IC50: 97

Isoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D Q08499

Human

IC50: 278

Phosphodiesterase/cAMP-specific 3',5'-cyclic phosphodiesterase 4A/cAMP-specific 3',5'-cyclic phosphodiesterase 4C/cAMP-specific 3',5'-cyclic phosphodiesterase 4D O89084 Q01063 Q3UEI1 Q8VBU5

Mouse

IC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P27815 Q07343 Q08493 Q08499

Human

Ki: 239 IC50: 1488 Kd: 2 EC50: 14

cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D P14270 P14644 P14646 P54748

Rat

Ki: 6 IC50: 34

cAMP-specific 3',5'-cyclic phosphodiesterase 4D Q08499

Human

Ki: 155 IC50: 2782 Kd: 9 EC50: 6

cAMP-specific 3',5'-cyclic phosphodiesterase 4D P14270

Rat

EC50: 3

cAMP-specific 3',5'-cyclic phosphodiesterase 4D Q01063

Mouse

IC50: 15

cAMP-specific 3',5'-cyclic phosphodiesterase 4D [372-376,381-715,S375G,I381V,S383G,G384S,V385H,K386M) Q08499

Human

IC50: 31

cAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741] Q08499

Human

IC50: 24

cAMP-specific 3',5'-cyclic phosphodiesterase 4D [538-740] Q08499

Human

IC50: 16

cAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D] Q08499

Human

IC50: 105

3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7B Q13946 Q9NP56

Human

Ki: 7 IC50: 483

High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B Q13946 Q9NP56

Human

Ki: 2 IC50: 45

cAMP-specific 3',5'-cyclic phosphodiesterase 7B Q9NP56

Human

Ki: 5 IC50: 428

cAMP-specific 3',5'-cyclic phosphodiesterase 7B [91-450] Q9NP56

Human

IC50: 10

3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE Q15125 Q60490 Q9UBM7

Ki: 174 IC50: 36

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Q15125

Human

Ki: 51 IC50: 33

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Q60490

Guinea pig

Ki: 123

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase Q15125 Q9UBM7

Human

IC50: 3

3-DEHYDROQUINATE DEHYDRATASE P05194 P15474 P9WPX7 Q48255

Ki: 78 Kd: 7

3-dehydroquinate dehydratase P15474

Streptomyces coelicolor

Ki: 18 Kd: 3

3-dehydroquinate dehydratase P05194

Escherichia coli (strain K12)

Ki: 2

3-dehydroquinate dehydratase P9WPX7

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 35 Kd: 1

3-dehydroquinate dehydratase Q48255

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)

Ki: 23 Kd: 3

3-dehydroquinate synthase P07639

Escherichia coli (strain K12)

Ki: 16 Koff: 4 Kon: 3

3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE P00347 P04035 P09610 P51639 Q01237 Q10283 Q1W675

Ki: 12 IC50: 1345 EC50: 140 ITC: 27

3-hydroxy-3-methylglutaryl-coenzyme A reductase P51639

Rat

Ki: 1 IC50: 951 EC50: 51

3-hydroxy-3-methylglutaryl-coenzyme A reductase P00347

Chinese hamster

EC50: 45

3-hydroxy-3-methylglutaryl-coenzyme A reductase Q01237

Mouse

IC50: 5

3-hydroxy-3-methylglutaryl-coenzyme A reductase Q10283

Fission yeast

IC50: 23

3-hydroxy-3-methylglutaryl-coenzyme A reductase P09610

Golden hamster

IC50: 15

3-hydroxy-3-methylglutaryl-coenzyme A reductase Q1W675

Pig

IC50: 52

3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) P04035

Human

Ki: 11 IC50: 299 EC50: 44 ITC: 27

3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2 O08756 Q99714

Ki: 11 IC50: 57 Kd: 8

3-hydroxyacyl-CoA dehydrogenase type-2 Q99714

Human

Ki: 11 IC50: 51 Kd: 8

3-hydroxyacyl-CoA dehydrogenase type-2 O08756

Mouse

IC50: 6

3-hydroxyacyl-[acyl-carrier-protein] dehydratase Q965D7

malaria parasite P. falciparum

Ki: 3 IC50: 25

3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE FABZ A0A0E3A638 B1JQH1 O25928

IC50: 24 Other: 22

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ O25928

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)

IC50: 16 Other: 22

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ A0A0E3A638

Francisella tularensis

IC50: 4

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175] B1JQH1

Yersinia pestis

IC50: 4

3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE P46952 P46953

IC50: 2

3-hydroxyanthranilate 3,4-dioxygenase P46952

Human

IC50: 1

3-hydroxyanthranilate 3,4-dioxygenase P46953

Rat

IC50: 1

3-isopropylmalate dehydrogenase Q5SIY4

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Ki: 1

3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 P56937

Human

IC50: 3

3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 P18405 P24008 P31214

Ki: 242 IC50: 657

3-oxo-5-alpha-steroid 4-dehydrogenase 1 P18405

Human

Ki: 181 IC50: 409

3-oxo-5-alpha-steroid 4-dehydrogenase 1 P24008

Rat

Ki: 6 IC50: 54

3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 P24008 P31214

Rat

Ki: 55 IC50: 194

3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 P24008 P31213 P31214

Ki: 155 IC50: 689

3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 P24008 P31214

Rat

Ki: 55 IC50: 194

3-oxo-5-alpha-steroid 4-dehydrogenase 2 P31213

Human

Ki: 96 IC50: 471

3-oxo-5-alpha-steroid 4-dehydrogenase 2 P31214

Rat

Ki: 4 IC50: 24

3-oxoacyl-ACP synthase A0A0C7ACN7

Pseudomonas aeruginosa

IC50: 41 Kd: 1

3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE Q8I2S7 Q965D6

Ki: 6 IC50: 24

3-oxoacyl-[acyl-carrier-protein] reductase Q8I2S7

Plasmodium falciparum (isolate 3D7)

IC50: 10

3-oxoacyl-acyl-carrier protein reductase Q965D6

malaria parasite P. falciparum

Ki: 6 IC50: 14

3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 P0A953 P9WQD8 P9WQD9

Ki: 23 IC50: 41 Kd: 18

3-oxoacyl-[acyl-carrier-protein] synthase 1 P9WQD8

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Ki: 22

3-oxoacyl-[acyl-carrier-protein] synthase 1 P9WQD9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 1 Kd: 18

3-oxoacyl-[acyl-carrier-protein] synthase 1 P0A953

Escherichia coli (strain K12)

IC50: 40

3-oxoacyl-[acyl-carrier-protein] synthase 1 [C171Q] P9WQD8

Mycobacterium tuberculosis

Ki: 1

3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 2 P9WQD7 Q5TKS0

IC50: 52 Kd: 24

3-oxoacyl-[acyl-carrier-protein] synthase 2 P9WQD7

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 38

3-oxoacyl-[acyl-carrier-protein] synthase 2 Q5TKS0

Staphylococcus aureus

IC50: 14 Kd: 24

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 O15530

Human

Ki: 13 IC50: 2244 Kd: 174 EC50: 28 ITC: 2

3-phosphoinositide dependent protein kinase-1 O15530

Human

Ki: 13 IC50: 1060 Kd: 161 EC50: 28 ITC: 2

3-phosphoinositide-dependent protein kinase 1 [409-556] O15530

Human

Kd: 11

3-phosphoinositide-dependent protein kinase 1 [48-359] O15530

Human

IC50: 35

3-phosphoinositide-dependent protein kinase 1 [50-359] O15530

Human

Kd: 2

3-phosphoinositide-dependent protein kinase 1 [51-359,A162V] O15530

Human

IC50: 2

3-phosphoinositide-dependent protein kinase 1 [51-359,E166D] O15530

Human

IC50: 2

3-phosphoinositide-dependent protein kinase 1 [51-359,L159M] O15530

Human

IC50: 2

3-phosphoinositide-dependent protein kinase 1 [51-359,T222A] O15530

Human

IC50: 2

3-phosphoinositide-dependent protein kinase 1 [51-359,V143T,T222A] O15530

Human

IC50: 2

3-phosphoinositide-dependent protein kinase 1 [51-359,V143T] O15530

Human

IC50: 2

3-phosphoinositide-dependent protein kinase 1 [51-359] O15530

Human

IC50: 806

3-phosphoinositide-dependent protein kinase 1 [51-360] O15530

Human

IC50: 331

3-phosphoshikimate 1-carboxyvinyltransferase P0A6D3

Escherichia coli (strain K12)

Ki: 30 IC50: 44 Kd: 17 Koff: 3 Kon: 4

3C-like protease Q3Y5H1

Avian infectious bronchitis virus

IC50: 101

4'-phosphopantetheinyl transferase PptT O33336

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 31

4,4'-DIAPOPHYTOENE DESATURASE (4,4'-DIAPONEUROSPORENE-FORMING) O07855 Q8NUQ6

IC50: 324

4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) O07855

Staphylococcus aureus (strain Newman)

IC50: 313

4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) Q8NUQ6

Staphylococcus aureus (strain MW2)

IC50: 11

4,4'-diapophytoene synthase A9JQL9

Staphylococcus aureus

Ki: 40 IC50: 53

4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL P50554 P61922 P80147 P80404 Q9BGI0

Ki: 95 IC50: 63 Kd: 2

4-aminobutyrate aminotransferase, mitochondrial Q9BGI0

Bovine

Ki: 1

4-aminobutyrate aminotransferase, mitochondrial P80147

Pig

Ki: 63 Kd: 2

4-aminobutyrate aminotransferase, mitochondrial P80404

Human

Ki: 26 IC50: 28

4-aminobutyrate aminotransferase, mitochondrial P61922

Mouse

IC50: 4

4-aminobutyrate aminotransferase, mitochondrial P50554

Rat

Ki: 5 IC50: 31

4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE P62615 Q8ZEY1

IC50: 10

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase P62615

Escherichia coli (strain K12)

IC50: 4

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Q8ZEY1

Yersinia pestis

IC50: 6

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic P93841

Tomato

IC50: 2

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 Q9Y231

Human

Ki: 7 IC50: 7

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 Q11128

Human

Ki: 2 IC50: 5

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 P51993

Human

Ki: 5 IC50: 8

4-hydroxy-2-oxoglutarate aldolase, mitochondrial Q86XE5

Human

Ki: 25

4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE O67625 P62623 Q9HVM7

Ki: 5 IC50: 21

4-hydroxy-3-methylbut-2-enyl diphosphate reductase Q9HVM7

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

Ki: 1

4-hydroxy-3-methylbut-2-enyl diphosphate reductase P62623

Escherichia coli (strain K12)

Ki: 1

4-hydroxy-3-methylbut-2-enyl diphosphate reductase O67625

Aquifex aeolicus (strain VF5)

Ki: 3 IC50: 21

4-hydroxy-tetrahydrodipicolinate reductase P04036

Escherichia coli (strain K12)

Ki: 4

4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE P0A6L2 Q04796

Ki: 11

4-hydroxy-tetrahydrodipicolinate synthase P0A6L2

Escherichia coli (strain K12)

Ki: 10

4-hydroxy-tetrahydrodipicolinate synthase Q04796

Bacillus subtilis (strain 168)

Ki: 1

4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic Q9LZX6

Arabidopsis thaliana

IC50: 2

4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic Q9FVC8

Arabidopsis thaliana

IC50: 2

4-HYDROXYPHENYLPYRUVATE DIOXYGENASE O23920 P32754 P32755 P93836 Q02110

Ki: 59 IC50: 231 Kd: 1

4-hydroxyphenylpyruvate dioxygenase Q02110

Pig

Ki: 1 IC50: 131

4-hydroxyphenylpyruvate dioxygenase P32755

Rat

IC50: 6

4-hydroxyphenylpyruvate dioxygenase P32754

Human

Ki: 45 IC50: 68

4-hydroxyphenylpyruvate dioxygenase P93836

Mouse-ear cress

Ki: 13 IC50: 26

4-hydroxyphenylpyruvate dioxygenase O23920

Wild carrot

Kd: 1

5' exonuclease Apollo Q9H816

Human

IC50: 3

5'-3' exonuclease PLD3 Q8IV08

Human

IC50: 4 EC50: 2

5'-3' exonuclease PLD4 Q96BZ4

Human

IC50: 4 EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1 Q13131

Human

IC50: 37 Kd: 132 EC50: 49

5'-AMP-activated protein kinase catalytic subunit alpha-1 P54645

Rat

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/catalytic subunit alpha-2/subunit beta-1/subunit beta-2/subunit gamma-1/subunit gamma-2/subunit gamma-3 O54950 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078

Mouse

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 P54619 Q13131 Q9Y478

Human

IC50: 15 Kd: 29 EC50: 335

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-2 Q13131 Q9UGJ0 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-3 Q13131 Q9UGI9 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 P54645 P80385 Q9QZH4

Rat

EC50: 3

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 O43741 P54619 Q13131

Human

Kd: 1 EC50: 9

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-3 O43741 Q13131 Q9UGI9

Human

EC50: 1

5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 O43741 O54950 P54619 P54646 Q09137 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078 Q9UGJ0 Q9Y478

Ki: 3 IC50: 25 Kd: 126 EC50: 1138

5'-AMP-activated protein kinase catalytic subunit alpha-1/catalytic subunit alpha-2/subunit beta-1/subunit beta-2/subunit gamma-1/subunit gamma-2/subunit gamma-3 O54950 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078

Mouse

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-2 P54646

Human

Ki: 3 IC50: 23 Kd: 126 EC50: 1007

5'-AMP-activated protein kinase catalytic subunit alpha-2 Q09137

Rat

EC50: 3

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1 P54619 P54646 Q9Y478

Human

IC50: 2 EC50: 125

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-2 P54646 Q9UGJ0 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-2/subunit gamma-2 O43741 P54646 Q9UGJ0

Human

EC50: 1

5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 O54950 P49760 P54619 P54646 P80386 Q13131 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078 Q9UGI9 Q9UGJ0 Q9Y478

Ki: 2 IC50: 43 Kd: 29 EC50: 468

5'-AMP-activated protein kinase catalytic subunit alpha-1/catalytic subunit alpha-2/subunit beta-1/subunit beta-2/subunit gamma-1/subunit gamma-2/subunit gamma-3 O54950 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078

Mouse

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 P54619 Q13131 Q9Y478

Human

IC50: 15 Kd: 29 EC50: 335

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-2 Q13131 Q9UGJ0 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-3 Q13131 Q9UGI9 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1 P54619 P54646 Q9Y478

Human

IC50: 2 EC50: 125

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-2 P54646 Q9UGJ0 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase subunit beta-1 Q9Y478

Human

Ki: 2 IC50: 20 EC50: 3

5'-AMP-activated protein kinase subunit beta-1 P80386

Rat

EC50: 1

5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2 P49760 P54619 Q9Y478

Human

IC50: 6

5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2 O43741 O54950 P54619 P54645 P54646 P80385 Q13131 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9QZH4 Q9R078 Q9UGI9 Q9UGJ0

IC50: 2 Kd: 1 EC50: 26

5'-AMP-activated protein kinase catalytic subunit alpha-1/catalytic subunit alpha-2/subunit beta-1/subunit beta-2/subunit gamma-1/subunit gamma-2/subunit gamma-3 O54950 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078

Mouse

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 P54645 P80385 Q9QZH4

Rat

EC50: 3

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 O43741 P54619 Q13131

Human

Kd: 1 EC50: 9

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-3 O43741 Q13131 Q9UGI9

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-2/subunit gamma-2 O43741 P54646 Q9UGJ0

Human

EC50: 1

5'-AMP-activated protein kinase subunit beta-2 Q9QZH4

Rat

IC50: 2

5'-AMP-activated protein kinase subunit beta-2 O43741

Human

EC50: 11

5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 O43741 O54950 P49760 P54619 P54645 P54646 P80385 Q13131 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9QZH4 Q9R078 Q9Y478

IC50: 24 Kd: 30 EC50: 483

5'-AMP-activated protein kinase catalytic subunit alpha-1/catalytic subunit alpha-2/subunit beta-1/subunit beta-2/subunit gamma-1/subunit gamma-2/subunit gamma-3 O54950 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078

Mouse

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 P54619 Q13131 Q9Y478

Human

IC50: 15 Kd: 29 EC50: 335

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 P54645 P80385 Q9QZH4

Rat

EC50: 3

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 O43741 P54619 Q13131

Human

Kd: 1 EC50: 9

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1 P54619 P54646 Q9Y478

Human

IC50: 2 EC50: 125

5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2 P49760 P54619 Q9Y478

Human

IC50: 6

5'-AMP-activated protein kinase subunit gamma-1 P54619

Human

IC50: 1 EC50: 9

5'-AMP-activated protein kinase subunit gamma-1 P80385

Rat

EC50: 1

5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-2 O43741 O54950 P54646 Q13131 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078 Q9UGJ0 Q9Y478

EC50: 5

5'-AMP-activated protein kinase catalytic subunit alpha-1/catalytic subunit alpha-2/subunit beta-1/subunit beta-2/subunit gamma-1/subunit gamma-2/subunit gamma-3 O54950 Q5EG47 Q6PAM0 Q8BGM7 Q8BRK8 Q91WG5 Q9R078

Mouse

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-2 Q13131 Q9UGJ0 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-2 P54646 Q9UGJ0 Q9Y478

Human

EC50: 1

5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-2/subunit gamma-2 O43741 P54646 Q9UGJ0

Human

EC50: 1

5'-AMP-activated protein kinase subunit gamma-2 Q9UGJ0

Human

EC50: 1

5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE B5Y1L0 C6S634 J7QX79 P0AF12 Q5HFG2

Ki: 50 Kd: 32

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12

Escherichia coli (strain K12)

Ki: 47 Kd: 8

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase C6S634

Neisseria meningitidis

Kd: 8

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase B5Y1L0

Klebsiella pneumoniae

Kd: 8

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q5HFG2

Staphylococcus aureus (Firmicutes)

Kd: 8

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase J7QX79

Escherichia coli

Ki: 3

5'-NUCLEOTIDASE P21588 P21589 Q61503

Ki: 248 IC50: 2670 EC50: 12

5'-nucleotidase P21589

Human

Ki: 122 IC50: 2563 EC50: 8

5'-nucleotidase P21588

Rat

Ki: 126 IC50: 77

5'-nucleotidase Q61503

Mouse

IC50: 30 EC50: 4

5,6-dihydroxyindole-2-carboxylic acid oxidase P07147

Mouse

IC50: 3

5-aminolevulinate synthase, erythroid-specific, mitochondrial P22557

Human

IC50: 6

5-HYDROXYMETHYL-DUMP N-HYDROLASE O35820 O43598

Ki: 57 Kd: 5 ITC: 5

2'-deoxynucleoside 5'-phosphate N-hydrolase 1 O43598

Human

Ki: 25

Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) O35820

Rat

Ki: 32 Kd: 5 ITC: 5

5-hydroxytryptamine 1D receptor Q8MI13

Bovine

Ki: 56 IC50: 16

5-hydroxytryptamine receptor 1A P08908

Human

Ki: 6644 IC50: 781 Kd: 17 EC50: 1430

5-hydroxytryptamine receptor 1A P19327

Rat

Ki: 4511 IC50: 1157 Kd: 4 EC50: 23

5-hydroxytryptamine receptor 1A G3I1B6

Chinese hamster

Ki: 53

5-hydroxytryptamine receptor 1A Q64264

Mouse

Ki: 70 IC50: 39 EC50: 1

5-hydroxytryptamine receptor 1A A0A1V4KRM0

pigeon

Ki: 6

5-hydroxytryptamine receptor 1A Q9MZ11

Rabbit

Ki: 7

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F P19327 P28564 P28565 P30940

Rat

Ki: 144 IC50: 138

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 1A/1B/1D/2C P08908 P28221 P28222 P28335

Human

Ki: 21

5-hydroxytryptamine receptor 1A/2C P08908 P28335

Human

Ki: 5

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F P19327 P28564 P28565 P30940

Rat

Ki: 144 IC50: 138

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 1A/1B/1D/2C P08908 P28221 P28222 P28335

Human

Ki: 21

5-hydroxytryptamine receptor 1B P28222

Human

Ki: 1266 IC50: 357 Kd: 1 EC50: 76

5-hydroxytryptamine receptor 1B P28564

Rat

Ki: 353 IC50: 239 Kd: 2 EC50: 2

5-hydroxytryptamine receptor 1B P46636

Chinese hamster

Ki: 54

5-hydroxytryptamine receptor 1B P28334

Mouse

Ki: 8

5-hydroxytryptamine receptor 1B P79250

Dog

Ki: 2

5-hydroxytryptamine receptor 1B L8IGV0

wild yak

Ki: 2

5-hydroxytryptamine receptor 1B O08892

Guinea pig

Ki: 5 Kd: 1

5-hydroxytryptamine receptor 1B A0A1V4JMG2

pigeon

Ki: 6

5-hydroxytryptamine receptor 1B P49144

Rabbit

Ki: 1

5-hydroxytryptamine receptor 1B P79399

Pig

Ki: 1

5-hydroxytryptamine receptor 1B Q9N2B7

Western lowland gorilla

Ki: 7

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F P19327 P28564 P28565 P30940

Rat

Ki: 144 IC50: 138

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 1A/1B/1D/2C P08908 P28221 P28222 P28335

Human

Ki: 21

5-hydroxytryptamine receptor 1D P28221

Human

Ki: 1305 IC50: 428 Kd: 5 EC50: 193

5-hydroxytryptamine receptor 1D Q61224

Mouse

Ki: 9

5-hydroxytryptamine receptor 1D A0A1U8CB25

Chinese hamster

Ki: 1

5-hydroxytryptamine receptor 1D P11614

Dog

Ki: 18

5-hydroxytryptamine receptor 1D Q60484

Guinea pig

Ki: 12 IC50: 5 EC50: 6

5-hydroxytryptamine receptor 1D A0A1V4JDN9

pigeon

Ki: 6

5-hydroxytryptamine receptor 1D P28565

Rat

Ki: 44 IC50: 25 EC50: 7

5-hydroxytryptamine receptor 1D P79400

Pig

Ki: 3 IC50: 173 Kd: 2

5-HYDROXYTRYPTAMINE RECEPTOR 1E A5X5Y0 F6XI83 G1TCS6 G5B6Z9 L8I6M5 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Ki: 315 IC50: 106 Kd: 3 EC50: 51

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1E P28566

Human

Ki: 303 IC50: 88 EC50: 51

5-hydroxytryptamine receptor 1E L8I6M5

wild yak

Ki: 1

5-hydroxytryptamine receptor 1E G5B6Z9

Rat

Ki: 6

G_PROTEIN_RECEP_F1_2 domain-containing protein G1TCS6

Rabbit

IC50: 3

G_PROTEIN_RECEP_F1_2 domain-containing protein F6XI83

Chinese hamster

Ki: 1

G_PROTEIN_RECEP_F1_2 domain-containing protein

Pig

Ki: 3

5-HYDROXYTRYPTAMINE RECEPTOR 1F A0A1U8CCS4 A5X5Y0 O95264 P08908 P08909 P14842 P19327 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30994 P31388 P32305 P34969 P35364 P35365 P35563 P41595 P46098 P47898 P50406 Q02284 Q13639 Q62758 Q70Z44 Q8WXA8 Q9JJ16

Ki: 377 IC50: 173 Kd: 3 EC50: 25

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F P19327 P28564 P28565 P30940

Rat

Ki: 144 IC50: 138

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 1F A0A1U8CCS4

Chinese hamster

Ki: 1

5-hydroxytryptamine receptor 1F P30939

Human

Ki: 210 IC50: 17 EC50: 25

5-hydroxytryptamine receptor 1F Q02284

Mouse

Ki: 10

5-hydroxytryptamine receptor 1F P30940

Rat

Ki: 9

5-HYDROXYTRYPTAMINE RECEPTOR 2A A0A1V4J4E5 A5X5Y0 G1SYA7 O46635 O95264 P08908 P08909 P14842 P19327 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30994 P31388 P32305 P34968 P34969 P35363 P35364 P35365 P35563 P41595 P46098 P47898 P49137 P50128 P50129 P50406 Q02152 Q13639 Q14416 Q62758 Q70Z44 Q75Z89 Q8WXA8 Q9JJ16

Ki: 9948 IC50: 2709 Kd: 29 EC50: 1318 ITC: 5

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 2A P28223

Human

Ki: 6310 IC50: 1503 Kd: 15 EC50: 1084 ITC: 5

5-hydroxytryptamine receptor 2A P14842

Rat

Ki: 2516 IC50: 497 Kd: 3 EC50: 127

5-hydroxytryptamine receptor 2A P35363

Mouse

Ki: 16 EC50: 62

5-hydroxytryptamine receptor 2A P50129

Pig

Ki: 105

5-hydroxytryptamine receptor 2A P50128

Rhesus macaque

Ki: 9

5-hydroxytryptamine receptor 2A Q75Z89

Bovine

Ki: 11 IC50: 144

5-hydroxytryptamine receptor 2A A0A1V4J4E5

pigeon

Ki: 6

5-hydroxytryptamine receptor 2A G1SYA7

Rabbit

Ki: 1

5-hydroxytryptamine receptor 2A O46635

Dog

Ki: 1 EC50: 5

5-hydroxytryptamine receptor 2A/2B/2C P34968 P35363 Q02152

Mouse

Ki: 151 IC50: 10

5-hydroxytryptamine receptor 2A/MAP kinase-activated protein kinase 2 P28223 P49137

Human

IC50: 8

5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2 P28223 Q14416

Human

Ki: 36 IC50: 74 EC50: 40

Serotonin 2 (5-HT2) receptor P08909 P14842 P30994

Rat

Ki: 710 IC50: 432 Kd: 5

Serotonin 2 (5-HT2) receptor P28223 P28335 P41595

Human

Ki: 73 IC50: 23 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 2A/2B/2C P34968 P35363 Q02152

Mouse

Ki: 151 IC50: 10

5-hydroxytryptamine receptor 2B P41595

Human

Ki: 1965 IC50: 260 EC50: 841

5-hydroxytryptamine receptor 2B Q02152

Mouse

Ki: 32 EC50: 3

5-hydroxytryptamine receptor 2B Q8MI09

Bovine

Ki: 31

5-hydroxytryptamine receptor 2B P30994

Rat

Ki: 143 Kd: 55 EC50: 19

Serotonin 2 (5-HT2) receptor P08909 P14842 P30994

Rat

Ki: 710 IC50: 432 Kd: 5

Serotonin 2 (5-HT2) receptor P28223 P28335 P41595

Human

Ki: 73 IC50: 23 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 1A/1B/1D/2C P08908 P28221 P28222 P28335

Human

Ki: 21

5-hydroxytryptamine receptor 1A/2C P08908 P28335

Human

Ki: 5

5-hydroxytryptamine receptor 2A/2B/2C P34968 P35363 Q02152

Mouse

Ki: 151 IC50: 10

5-hydroxytryptamine receptor 2C P28335

Human

Ki: 3588 IC50: 980 Kd: 5 EC50: 1379

5-hydroxytryptamine receptor 2C P08909

Rat

Ki: 1056 IC50: 44 Kd: 2 EC50: 55

5-hydroxytryptamine receptor 2C P34968

Mouse

Ki: 13

5-hydroxytryptamine receptor 2C Q60F97

Dog

Ki: 2 EC50: 2

5-hydroxytryptamine receptor 2C G7ZKZ7

Pig

Ki: 57

5-hydroxytryptamine receptor 2C K7GSR7

Pig

Ki: 15

Serotonin 2 (5-HT2) receptor P08909 P14842 P30994

Rat

Ki: 710 IC50: 432 Kd: 5

Serotonin 2 (5-HT2) receptor P28223 P28335 P41595

Human

Ki: 73 IC50: 23 Kd: 3

5-hydroxytryptamine receptor 2C isoform A A0A1V4KYG9

pigeon

Ki: 6

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 3A P23979

Mouse

Ki: 183 Kd: 1 EC50: 6

5-hydroxytryptamine receptor 3A P46098

Human

Ki: 817 IC50: 805 Kd: 4 EC50: 29

5-hydroxytryptamine receptor 3A F1N4Y2

Bovine

Ki: 1

5-hydroxytryptamine receptor 3A O70212

Guinea pig

Ki: 52 IC50: 19 Kd: 2 EC50: 2

5-hydroxytryptamine receptor 3A A0A218UVI3

pigeon

Ki: 6

5-hydroxytryptamine receptor 3A P35563

Rat

Ki: 201 IC50: 11 Kd: 3 EC50: 3

5-hydroxytryptamine receptor 3A P23979

Mus musculus

IC50: 2

5-hydroxytryptamine receptor 3A/3B P35563 Q9JJ16

Rat

Ki: 754 IC50: 405

5-hydroxytryptamine receptor 3A/3B O95264 P46098

Human

Ki: 1 IC50: 3 Kd: 2 EC50: 19

5-hydroxytryptamine receptor 3A/3B P23979 Q9JHJ5

Mouse

Ki: 2 Kd: 15

5-hydroxytryptamine receptor 3A/3B/3C/3D/3E A5X5Y0 O95264 P46098 Q70Z44 Q8WXA8

Human

Ki: 84 IC50: 38

5-hydroxytryptamine receptor 3A/3C P46098 Q8WXA8

Human

IC50: 1

5-hydroxytryptamine receptor 3A/3E A5X5Y0 P46098

Human

IC50: 1

5-HYDROXYTRYPTAMINE RECEPTOR 3B A5X5Y0 O95264 P08908 P08909 P14842 P19327 P23979 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30994 P31388 P32305 P34969 P35364 P35365 P35563 P41595 P46098 P47898 P50406 Q13639 Q62758 Q70Z44 Q8WXA8 Q9JHJ5 Q9JJ16

Ki: 854 IC50: 464 Kd: 20 EC50: 19

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 3A/3B P35563 Q9JJ16

Rat

Ki: 754 IC50: 405

5-hydroxytryptamine receptor 3A/3B O95264 P46098

Human

Ki: 1 IC50: 3 Kd: 2 EC50: 19

5-hydroxytryptamine receptor 3A/3B P23979 Q9JHJ5

Mouse

Ki: 2 Kd: 15

5-hydroxytryptamine receptor 3A/3B/3C/3D/3E A5X5Y0 O95264 P46098 Q70Z44 Q8WXA8

Human

Ki: 84 IC50: 38

5-hydroxytryptamine receptor 3B Q9JHJ5

Mouse

Ki: 10

5-HYDROXYTRYPTAMINE RECEPTOR 3C A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 85 IC50: 54 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 3A/3B/3C/3D/3E A5X5Y0 O95264 P46098 Q70Z44 Q8WXA8

Human

Ki: 84 IC50: 38

5-hydroxytryptamine receptor 3A/3C P46098 Q8WXA8

Human

IC50: 1

5-HYDROXYTRYPTAMINE RECEPTOR 3D A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 85 IC50: 53 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 3A/3B/3C/3D/3E A5X5Y0 O95264 P46098 Q70Z44 Q8WXA8

Human

Ki: 84 IC50: 38

5-HYDROXYTRYPTAMINE RECEPTOR 3E A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 85 IC50: 54 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 3A/3B/3C/3D/3E A5X5Y0 O95264 P46098 Q70Z44 Q8WXA8

Human

Ki: 84 IC50: 38

5-hydroxytryptamine receptor 3A/3E A5X5Y0 P46098

Human

IC50: 1

5-HYDROXYTRYPTAMINE RECEPTOR 4 A5X5Y0 O70528 O95264 P08908 P08909 P14842 P19327 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30994 P31388 P32305 P34969 P35364 P35365 P35563 P41595 P46098 P47898 P50406 P97288 Q13639 Q29006 Q62758 Q6Q253 Q70Z44 Q8WXA8 Q9JJ16

Ki: 1321 IC50: 209 Kd: 9 EC50: 534 Other: 1

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 4 Q13639

Human

Ki: 586 IC50: 86 Kd: 3 EC50: 380 Other: 1

5-hydroxytryptamine receptor 4 O70528

Guinea pig

Ki: 319 IC50: 94 Kd: 1 EC50: 58

5-hydroxytryptamine receptor 4 P97288

Mouse

Ki: 65 IC50: 1 EC50: 2

5-hydroxytryptamine receptor 4 Q29006

Pig

Ki: 4

5-hydroxytryptamine receptor 4 Q62758

Rat

Ki: 336 IC50: 9 EC50: 94

5-hydroxytryptamine receptor 4 Q6Q253

Pig

Ki: 7 Kd: 2

Isoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (H5-HT4(g)) Q13639

Human

Ki: 1 IC50: 1

5-HYDROXYTRYPTAMINE RECEPTOR 5A A5X5Y0 L8HQU1 O95264 P08908 P08909 P14842 P19327 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30966 P30994 P31388 P32305 P34969 P35364 P35365 P35563 P41595 P46098 P47898 P50406 Q13639 Q62758 Q70Z44 Q8WXA8 Q9JJ16

Ki: 636 IC50: 67 Kd: 3 EC50: 2

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 5A P47898

Human

Ki: 484 IC50: 49 EC50: 2

5-hydroxytryptamine receptor 5A P30966

Mouse

Ki: 100

5-hydroxytryptamine receptor 5A L8HQU1

wild yak

Ki: 1

5-hydroxytryptamine receptor 5A P35364

Rat

Ki: 48

5-HYDROXYTRYPTAMINE RECEPTOR 5B P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31387 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Ki: 83 IC50: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 5B P31387

Mouse

Ki: 26

5-hydroxytryptamine receptor 5B P35365

Rat

Ki: 55

5-HYDROXYTRYPTAMINE RECEPTOR 6 A5X5Y0 L8HST4 O95264 P08908 P08909 P14842 P19327 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30994 P31388 P32305 P34969 P35364 P35365 P35563 P41595 P46098 P47898 P50406 Q13639 Q62758 Q70Z44 Q8WXA8 Q9JJ16 Q9R1C8

Ki: 5069 IC50: 1031 Kd: 3 EC50: 128 Other: 3

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 6 P50406

Human

Ki: 4746 IC50: 1010 EC50: 128 Other: 3

5-hydroxytryptamine receptor 6 L8HST4

wild yak

Ki: 1

5-hydroxytryptamine receptor 6 Q9R1C8

Mouse

Ki: 57

5-hydroxytryptamine receptor 6 P31388

Rat

Ki: 262 IC50: 3

5-HYDROXYTRYPTAMINE RECEPTOR 7 A5X5Y0 L8II28 O95264 P08908 P08909 P14842 P19327 P28221 P28222 P28223 P28335 P28564 P28565 P28566 P30939 P30940 P30994 P31388 P32304 P32305 P34969 P35364 P35365 P35563 P41595 P46098 P47898 P50406 P50407 Q13639 Q62758 Q70Z44 Q8WXA8 Q9JJ16

Ki: 4930 IC50: 1112 Kd: 6 EC50: 301

5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7 A5X5Y0 O95264 P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P46098 P47898 P50406 Q13639 Q70Z44 Q8WXA8

Human

Ki: 1 IC50: 15 Kd: 3

5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7 P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 P35365 P35563 Q62758 Q9JJ16

Rat

Ki: 2 IC50: 3

5-hydroxytryptamine receptor 7 P32305

Rat

Ki: 1359 IC50: 4

5-hydroxytryptamine receptor 7 P34969

Human

Ki: 3422 IC50: 1090 Kd: 3 EC50: 296

5-hydroxytryptamine receptor 7 P32304

Mouse

Ki: 39

5-hydroxytryptamine receptor 7 L8II28

wild yak

Ki: 1

5-hydroxytryptamine receptor 7 P50407

Guinea pig

Ki: 106 EC50: 5

5-lipoxygenase Q9BEG3

Bovine

IC50: 235

6,7-dimethyl-8-ribityllumazine synthase P9WHE9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 21

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 P16118

Human

IC50: 37

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 O60825

Human

IC50: 36

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Q16875

Human

Ki: 4 IC50: 281

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 Q16877

Human

IC50: 105

6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING P00349 P52209 P85968 Q38DI7

Ki: 46 IC50: 21 Kd: 1

6-phosphogluconate dehydrogenase, decarboxylating P52209

Human

Ki: 33 IC50: 19 Kd: 1

6-phosphogluconate dehydrogenase, decarboxylating P85968

Rat

Ki: 1 IC50: 1

6-phosphogluconate dehydrogenase, decarboxylating P00349

Sheep

Ki: 8

6-phosphogluconate dehydrogenase, decarboxylating Q38DI7

Trypanosoma brucei brucei (strain 927/4 GUTat10.1)

Ki: 4 IC50: 1

6-phosphogluconolactonase Q9GRG6

Trypanosoma brucei

Kd: 1

6-pyruvoyl tetrahydrobiopterin synthase Q03393

Human

IC50: 3

60 kDa heat shock protein, mitochondrial P10809

Human

IC50: 368

7-DEHYDROCHOLESTEROL REDUCTASE Q15125 Q9UBM7 Q9Z2Z8

Ki: 6 IC50: 35 Kd: 1

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase Q15125 Q9UBM7

Human

IC50: 3

7-dehydrocholesterol reductase Q9Z2Z8

Rat

Ki: 6

7-dehydrocholesterol reductase Q9UBM7

Human

IC50: 32 Kd: 1

7-methylguanosine phosphate-specific 5'-nucleotidase Q969T7

Human

IC50: 2

72 KDA TYPE IV COLLAGENASE P03956 P08253 P14780 P22894 P33434 P33436 P45452 Q95JA4

Ki: 1386 IC50: 4554 Kd: 11

72 kDa type IV collagenase P33436

Rat

IC50: 19

72 kDa type IV collagenase Q95JA4

Pig

IC50: 20

72 kDa type IV collagenase P33434

Mouse

IC50: 3

72 kDa type IV collagenase (MMP2) P08253

Human

Ki: 1318 IC50: 4506 Kd: 11

72 kDa type IV collagenase/Collagenase 3/Interstitial collagenase/Matrix metalloproteinase-9/Neutrophil collagenase P03956 P08253 P14780 P22894 P45452

Human

Ki: 68 IC50: 6

85/88 kDa calcium-independent phospholipase A2 O60733

Human

IC50: 63

Curated by BindingDB

Curated by ChEMBL