BDB TargetNames

Target Names are taken from UniProtKB. To view the associated UniProt page, click on the UniProt ID. When we have data for a given Target in multiple species or for mutants of a given Target, we provide a header row (upper case, bold font) with all of the data followed by a separate for each species or variant of the Target.

Target Name
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Target Name

Organism

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UniProts

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IAG-nucleoside hydrolase Q9GPQ4

Trypanosoma vivax

Ki: 23

IgA-specific serine endopeptidase autotransporter P09790

Neisseria gonorrhoeae

IC50: 45

IGF-like family receptor 1 Q9H665

Human

IC50: 1 Kd: 1

IgG receptor FcRn large subunit p51 P55899

Human

IC50: 208 Kd: 204

ILEAL SODIUM/BILE ACID COTRANSPORTER P70172 Q12908 Q62633

Ki: 52 IC50: 320

Ileal sodium/bile acid cotransporter Q12908

Human

Ki: 51 IC50: 307

Ileal sodium/bile acid cotransporter P70172

Mouse

Ki: 1 IC50: 8

Ileal sodium/bile acid cotransporter Q62633

Rat

IC50: 5

IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE P03366 P06633 P0CO23

Ki: 26 IC50: 32

Gag-Pol polyprotein [600-1159,Y780C]/Imidazoleglycerol-phosphate dehydratase [600-1029,Y780C] P03366 P06633

Human immunodeficiency virus type 1

IC50: 3

Imidazoleglycerol-phosphate dehydratase P0CO23

Cryptococcus neoformans

Ki: 26 IC50: 29

Imipenem-hydrolyzing beta-lactamase P52663

Enterobacter cloacae

IC50: 14

Immunoglobulin A1 protease autotransporter P44969

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

IC50: 2

Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E] P01857 Q15116 Q9NZQ7

Human

IC50: 58

Immunoglobulin lambda variable 6-57 P01721

Human

EC50: 81

Immunoglobulin superfamily member 11 Q5DX21

Human

Kd: 1

Importin subunit alpha-1 P52292

Human

EC50: 1011

Caspase-1/Caspase-10/Caspase-14/Caspase-2/Caspase-3/Caspase-4/Caspase-5/Caspase-6/Caspase-7/Caspase-8/Caspase-9/Inactive caspase-12 P29466 P31944 P42574 P42575 P49662 P51878 P55210 P55211 P55212 Q14790 Q6UXS9 Q92851

Human

EC50: 1

Inactive phospholipase C-like protein 1 Q62688

Rat

IC50: 3

Inactive serine/threonine-protein kinase 19 P49842

Human

IC50: 17

Inactive tyrosine-protein kinase PEAK1 Q9H792

Human

IC50: 3

Inactive tyrosine-protein kinase transmembrane receptor ROR1 Q01973

Human

IC50: 13 Kd: 4

INDOLEAMINE 2,3-DIOXYGENASE 1 A0A8C0MXE9 P14902 P28776 Q9ERD9

Ki: 194 IC50: 6126 Kd: 68 EC50: 320 Other: 17

Indoleamine 2,3-dioxygenase 1 A0A8C0MXE9

Dog

IC50: 2

Indoleamine 2,3-dioxygenase 1 P14902

Human

Ki: 194 IC50: 5963 Kd: 68 EC50: 317 Other: 17

Indoleamine 2,3-dioxygenase 1 Q9ERD9

Rat

IC50: 1

Indoleamine 2,3-dioxygenase 1 P28776

Mouse

IC50: 160 EC50: 3

INDOLEAMINE 2,3-DIOXYGENASE 2 Q6ZQW0 Q8R0V5

Ki: 24 IC50: 136

Indoleamine 2,3-dioxygenase 2 Q8R0V5

Mouse

IC50: 48

Indoleamine 2,3-dioxygenase 2 Q6ZQW0

Human

Ki: 24 IC50: 88

INDOLETHYLAMINE N-METHYLTRANSFERASE O95050 O97972

Ki: 5 IC50: 127

Indolethylamine N-methyltransferase O95050

Human

Ki: 5 IC50: 45

Indolethylamine N-methyltransferase O97972

Rabbit

IC50: 82

INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 O43521 P68187 Q07820 Q13794 Q16611

Human

Ki: 4997 IC50: 6935 Kd: 96 EC50: 91 ITC: 6

Bcl-2 homologous antagonist/killer/Induced myeloid leukemia cell differentiation protein Mcl-1 Q07820 Q16611

Human

IC50: 1

Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] O43521 Q07820

Human

Ki: 163 IC50: 2687

Induced myeloid leukemia cell differentiation protein Mcl-1 [171-323] Q07820

Human

IC50: 56

Induced myeloid leukemia cell differentiation protein Mcl-1 Q07820

Human

Ki: 4550 IC50: 2387 Kd: 90 EC50: 91

Induced myeloid leukemia cell differentiation protein Mcl-1 (aa 172-327) Q07820

Human

Ki: 276 Kd: 6 ITC: 6

Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] Q07820

Human

Ki: 8 IC50: 1437

Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide P68187 Q07820 Q13794

Human

IC50: 290

Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43] Q07820 Q13794

Human

IC50: 77

Induced myeloid leukemia cell differentiation protein Mcl-1 homolog P97287

Mouse

Ki: 62 IC50: 65 Kd: 8 ITC: 10

Inhibin alpha chain P05111

Human

IC50: 1

Inhibin beta A chain Q04998

Mouse

IC50: 11

Inhibitor of growth protein 2 Q9H160

Human

IC50: 4 Kd: 3

INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT ALPHA O14920 O15111 Q9Y6K9

Human

Ki: 60 IC50: 515 Kd: 79

Inhibitor of nuclear factor kappa-B kinase subunit alpha O15111

Human

Ki: 60 IC50: 462 Kd: 79

Inhibitor of nuclear factor kappa-B kinase subunit alpha/Inhibitor of nuclear factor kappa-B kinase subunit beta/NF-kappa-B essential modulator O14920 O15111 Q9Y6K9

Human

IC50: 53

INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA O14920 O15111 O88351 Q9Y6K9

Ki: 262 IC50: 1650 Kd: 80

Inhibitor of nuclear factor kappa-B kinase subunit alpha/Inhibitor of nuclear factor kappa-B kinase subunit beta/NF-kappa-B essential modulator O14920 O15111 Q9Y6K9

Human

IC50: 53

Inhibitor of nuclear factor kappa-B kinase subunit beta O14920

Human

Ki: 262 IC50: 1570 Kd: 80

Inhibitor of nuclear factor kappa-B kinase subunit beta O88351

Mouse

IC50: 27

INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT EPSILON Q14164 Q9UHD2

Human

IC50: 2540 Kd: 130

Inhibitor of nuclear factor kappa-B kinase subunit epsilon Q14164

Human

IC50: 2514 Kd: 130

Inhibitor of nuclear factor kappa-B kinase subunit epsilon/Serine/threonine-protein kinase TBK1 Q14164 Q9UHD2

Human

IC50: 26

Inner capsid protein sigma-2 P11314

T1L

Ki: 1

INNER CENTROMERE PROTEIN Q96GD4 Q9NQS7 Q9UQB9

Human

Ki: 27 IC50: 90

Aurora kinase B [2-344]/Inner centromere protein [826-918] Q96GD4 Q9NQS7

Human

IC50: 1

Aurora kinase B/Inner centromere protein Q96GD4 Q9NQS7

Human

Ki: 26 IC50: 88

Aurora kinase C/Inner centromere protein Q9NQS7 Q9UQB9

Human

Ki: 1 IC50: 1

INORGANIC PYROPHOSPHATASE P00817 P0A7A9 P9WI55

IC50: 52

Inorganic pyrophosphatase P9WI55

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 24

Inorganic pyrophosphatase P0A7A9

Escherichia coli (strain K12)

IC50: 14

Inorganic pyrophosphatase P00817

Baker's yeast

IC50: 14

Inosine triphosphate pyrophosphatase Q9BY32

Human

IC50: 1

INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE A0A6L8P2U9 B5Z7J4 P0ADG7 P0C0H6 P49058 P9WKI7 Q5KP44 Q8T6T2 Q9HXM5

Ki: 77 IC50: 463 EC50: 1

Inosine-5'-monophosphate dehydrogenase Q8T6T2

Cryptosporidium parvum

Ki: 29 IC50: 388 EC50: 1

Inosine-5'-monophosphate dehydrogenase B5Z7J4

Helicobacter pylori (strain G27)

IC50: 9

Inosine-5'-monophosphate dehydrogenase P49058

Borrelia burgdorferi

IC50: 8

Inosine-5'-monophosphate dehydrogenase P0C0H6

Streptococcus pyogenes (Firmicutes)

IC50: 9

Inosine-5'-monophosphate dehydrogenase Q9HXM5

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

IC50: 16

Inosine-5'-monophosphate dehydrogenase P0ADG7

Escherichia coli (strain K12)

Ki: 32

Inosine-5'-monophosphate dehydrogenase A0A6L8P2U9

Bacillus anthracis

Ki: 12 IC50: 17

Inosine-5'-monophosphate dehydrogenase P9WKI7

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 4

Inosine-5'-monophosphate dehydrogenase Q5KP44

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 /ATCC MYA-565) (Filobasidiella neoformans)

IC50: 16

INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 P12268 P20839

Human

Ki: 104 IC50: 70 EC50: 1

Inosine-5'-monophosphate dehydrogenase 1 P20839

Human

Ki: 96 IC50: 40 EC50: 1

Inosine-5'-monophosphate dehydrogenase 1/2 P12268 P20839

Human

Ki: 8 IC50: 30

INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 P12268 P20839 P24547

Ki: 213 IC50: 802 EC50: 24

Inosine-5'-monophosphate dehydrogenase 1/2 P12268 P20839

Human

Ki: 8 IC50: 30

Inosine-5'-monophosphate dehydrogenase 2 P12268

Human

Ki: 201 IC50: 763 EC50: 24

Inosine-5'-monophosphate dehydrogenase 2 P24547

Mouse

Ki: 4 IC50: 9

Inosine-5-monophosphate dehydrogenase Q5CPK7

Cryptosporidium parvum

IC50: 4

Inosine-adenosine-guanosine-nucleoside hydrolase O15727

Trypanosoma brucei brucei

Ki: 4

Inosine-uridine preferring nucleoside hydrolase Q27546

Crithidia fasciculata

Ki: 4

INOSITOL 1,4,5-TRISPHOSPHATE-GATED CALCIUM CHANNEL ITPR1 P29994 Q14571 Q14573 Q14643

Ki: 1 IC50: 1 Kd: 58 EC50: 62

Inositol 1,4,5-trisphosphate receptor type 1 Q14643

Human

IC50: 1 Kd: 10

Inositol 1,4,5-trisphosphate receptor type 1 P29994

Rat

Kd: 48 EC50: 59

Inositol 1,4,5-trisphosphate receptor type 1/2/3 Q14571 Q14573 Q14643

Human

Ki: 1 EC50: 3

INOSITOL 1,4,5-TRISPHOSPHATE-GATED CALCIUM CHANNEL ITPR2 Q14571 Q14573 Q14643

Human

Ki: 1 IC50: 6 EC50: 3

Inositol 1,4,5-trisphosphate receptor type 1/2/3 Q14571 Q14573 Q14643

Human

Ki: 1 EC50: 3

Inositol 1,4,5-trisphosphate receptor type 2 Q14571

Human

IC50: 6

INOSITOL 1,4,5-TRISPHOSPHATE-GATED CALCIUM CHANNEL ITPR3 Q14571 Q14573 Q14643 Q8WN95

Ki: 2 IC50: 13 Kd: 4 EC50: 4

Inositol 1,4,5-trisphosphate receptor type 1/2/3 Q14571 Q14573 Q14643

Human

Ki: 1 EC50: 3

Inositol 1,4,5-trisphosphate receptor type 3 Q14573

Human

IC50: 5 Kd: 4 EC50: 1

Inositol 1,4,5-trisphosphate receptor type 3 Q8WN95

Bovine

Ki: 1 IC50: 8

Inositol hexakisphosphate kinase 1 Q92551

Human

Ki: 1 IC50: 127

Inositol hexakisphosphate kinase 2 Q9UHH9

Human

Ki: 1 IC50: 67 Kd: 1

Inositol hexakisphosphate kinase 3 Q96PC2

Human

Ki: 1 IC50: 50

Inositol monophosphatase 1 P20456

Bovine

IC50: 38

Inositol phosphorylceramide synthase O13332

Yeast

Ki: 7 IC50: 3

Inositol phosphorylceramide synthase catalytic subunit AUR1 P36107

Baker's yeast

Ki: 2 IC50: 6

Inositol polyphosphate multikinase Q8NFU5

Human

IC50: 17

Inositol polyphosphate-5-phosphatase A Q14642

Human

Ki: 11 IC50: 6

Inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) Q93YN9

Mouse-ear cress

Kd: 5 ITC: 5

Inositol-tetrakisphosphate 1-kinase Q13572

Human

Ki: 2

INOSITOL-TRISPHOSPHATE 3-KINASE A P17105 P23677

Ki: 1 IC50: 34

Inositol-trisphosphate 3-kinase A P23677

Human

Ki: 1 IC50: 25

Inositol-trisphosphate 3-kinase A P17105

Rat

IC50: 9

Inositol-trisphosphate 3-kinase C Q80ZG2

Rat

Ki: 1

INSULIN RECEPTOR P06213 P15127 P15208

Ki: 13 IC50: 1383 Kd: 132 EC50: 74

Insulin receptor P15127

Rat

IC50: 2

Insulin receptor P06213

Human

Ki: 13 IC50: 1188 Kd: 132 EC50: 31

Insulin receptor P15208

Mouse

IC50: 19 EC50: 43

Insulin receptor [964-1370] P06213

Human

IC50: 174

INSULIN RECEPTOR SUBSTRATE 1 P35568 P35570

Ki: 1 Kd: 9

Insulin receptor substrate 1 P35570

Rat

Ki: 1

Insulin receptor substrate 1 [1-264] P35568

Human

Kd: 9

Insulin receptor-related protein P14616

Human

IC50: 12 Kd: 118

INSULIN-DEGRADING ENZYME P14735 Q9JHR7

Ki: 37 IC50: 216 Kd: 1 EC50: 23

Insulin-degrading enzyme P14735

Human

Ki: 37 IC50: 200 Kd: 1 EC50: 23

Insulin-degrading enzyme Q9JHR7

Mouse

IC50: 16

INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR P08069 P24062 Q60751

Ki: 64 IC50: 2699 Kd: 119 EC50: 6

Insulin-like growth factor 1 receptor P08069

Human

Ki: 63 IC50: 2664 Kd: 119 EC50: 6

Insulin-like growth factor 1 receptor Q60751

Mouse

IC50: 35

Insulin-like growth factor 1 receptor P24062

Rat

Ki: 1

Insulin-like growth factor 2 mRNA-binding protein 1 Q9NZI8

Human

Kd: 3

Insulin-like growth factor-binding protein 1 P08833

Human

Ki: 2

Insulin-like growth factor-binding protein 2 P18065

Human

Ki: 2

Insulin-like growth factor-binding protein 3 P17936

Human

Ki: 46

Insulin-like growth factor-binding protein 4 P22692

Human

Ki: 2

Insulin-like growth factor-binding protein 5 P24593

Human

Ki: 11 Kd: 26

Insulin-like growth factor-binding protein 6 P24592

Human

Ki: 2

INTEGRASE P89582 Q76353 Q7ZJM1 T1QYY3

Ki: 27 IC50: 7353 Kd: 48 EC50: 79

Integrase P89582

Human immunodeficiency virus 2

IC50: 8 EC50: 1

Integrase Q7ZJM1

Human immunodeficiency virus type 1

Ki: 3 IC50: 2928 Kd: 27 EC50: 7

Integrase Q76353

Human immunodeficiency virus type 1

Ki: 22 IC50: 4345 Kd: 21 EC50: 70

Integrase T1QYY3

Human immunodeficiency virus type 1

Ki: 2 IC50: 72 EC50: 1

INTEGRIN ALPHA-1 P05556 P56199

Human

IC50: 1

Integrin alpha-1/beta-1 P05556 P56199

Human

IC50: 1

Integrin alpha-1/beta-1 [T112H] P05556 P56199

Human

Integrin alpha-10/beta-1 O75578 P05556

Human

IC50: 1

INTEGRIN ALPHA-2 P05106 P05556 P17301

Human

IC50: 120 EC50: 2

Integrin alpha-2 P17301

Human

IC50: 3

Integrin alpha-2 P17301

Human

IC50: 6

Integrin alpha-2/beta-1 P05556 P17301

Human

IC50: 47 EC50: 2

Integrin alpha-2/beta-1 [T112H] P05556 P17301

Human

IC50: 33

Integrin alpha-2/beta-3 P05106 P17301

Human

IC50: 31

INTEGRIN ALPHA-3 P05106 P26006

Human

IC50: 54 Kd: 1

Integrin alpha-3 P26006

Human

IC50: 7 Kd: 1

Integrin alpha-3/beta-3 P05106 P26006

Human

IC50: 47

INTEGRIN ALPHA-4 P05556 P13612 P19320 P26010 P26011 Q00651 Q13477 Q61826

Ki: 44 IC50: 2967 Kd: 1 EC50: 92 Other: 3

Integrin alpha-4 P13612

Human

IC50: 232 EC50: 75

Integrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1 P05556 P13612 P19320

Human

IC50: 40

Integrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1 P13612 P26010 Q61826

Human

IC50: 153

Integrin alpha-4/beta-1 P05556 P13612

Human

IC50: 1793 Kd: 1 EC50: 16

Integrin alpha-4/beta-1 [T112H] P05556 P13612

Human

Ki: 44 IC50: 201 Other: 3

Integrin alpha-4/beta-7 P13612 P26010

Human

IC50: 506 EC50: 1

Integrin alpha-4/beta-7 P26011 Q00651

Mouse

IC50: 4

Mucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7 P13612 P26010 Q13477

Human

IC50: 38

INTEGRIN ALPHA-5 P05556 P06756 P08648 P18564 P26012 P53708

Human

Ki: 7 IC50: 916 Kd: 4 EC50: 19

Integrin alpha-5 P08648

Human

Ki: 7 IC50: 12

Integrin alpha-5/alpha-8 P08648 P53708

Human

IC50: 28

Integrin alpha-5/alpha-V P06756 P08648

Human

IC50: 30

Integrin alpha-5/beta-1 P05556 P08648

Human

IC50: 597 Kd: 4 EC50: 19

Integrin alpha-5/beta-1 [T112H] P05556 P08648

Human

IC50: 70

Integrin alpha-5/beta-6 P08648 P18564

Human

IC50: 175

Integrin alpha-5/beta-6/beta-8 P08648 P18564 P26012

Human

IC50: 1

Integrin alpha-5/beta-8 P08648 P26012

Human

IC50: 3

INTEGRIN ALPHA-8 P05556 P08648 P53708

Human

IC50: 45

Integrin alpha-5/alpha-8 P08648 P53708

Human

IC50: 28

Integrin alpha-8/beta-1 P05556 P53708

Human

IC50: 17

INTEGRIN ALPHA-IIB O54890 P05106 P08514 Q9QUM0

Ki: 203 IC50: 2700 Kd: 115 EC50: 21

Integrin alpha-IIb P08514

Human

IC50: 61

Integrin alpha-IIb/beta-3 P05106 P08514

Human

Ki: 203 IC50: 2638 Kd: 115 EC50: 21

Integrin alpha-IIb/beta-3 O54890 Q9QUM0

Mouse

IC50: 1

INTEGRIN ALPHA-L P05107 P05362 P20701 P24063

IC50: 721 Kd: 54 EC50: 28

Integrin alpha-L P24063

Mouse

IC50: 3 EC50: 15

Integrin alpha-L P20701

Human

IC50: 170 Kd: 4

Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 P05107 P05362 P20701

Human

IC50: 331

Integrin alpha-L/Intercellular adhesion molecule 1 P05362 P20701

Human

IC50: 101 EC50: 2

Integrin alpha-L/beta-2 P05107 P20701

Human

IC50: 116 Kd: 50 EC50: 11

Integrin alpha-M/beta-2 P05107 P11215

Human

IC50: 6 EC50: 12

INTEGRIN ALPHA-V O54890 P05106 P05556 P06756 P08648 P18084 P18564 P26012 P43406

Ki: 257 IC50: 4842 Kd: 13 EC50: 53

Integrin alpha-5/alpha-V P06756 P08648

Human

IC50: 30

Integrin alpha-V P43406

Mouse

IC50: 1

Integrin alpha-V P06756

Human

IC50: 86

Integrin alpha-V/beta-1 P05556 P06756

Human

Ki: 3 IC50: 253 Kd: 2

Integrin alpha-V/beta-3 P05106 P06756

Human

Ki: 228 IC50: 2042 Kd: 5 EC50: 23

Integrin alpha-V/beta-3 O54890 P43406

Mouse

IC50: 1

Integrin alpha-V/beta-3/beta-5 P05106 P06756 P18084

Human

IC50: 8

Integrin alpha-V/beta-5 P06756 P18084

Human

Ki: 5 IC50: 577 Kd: 2 EC50: 14

Integrin alpha-V/beta-6 P06756 P18564

Human

Ki: 21 IC50: 1571 Kd: 2 EC50: 16

Integrin alpha-V/beta-8 P06756 P26012

Human

IC50: 273 Kd: 2

INTEGRIN BETA Q9TUN3 Q9TUN4

Rabbit

IC50: 16

Glycoprotein IIb/Integrin beta Q9TUN3 Q9TUN4

Rabbit

IC50: 1

Integrin beta Q9TUN3

Rabbit

IC50: 15

INTEGRIN BETA-1 O75578 P05556 P06756 P08648 P13612 P17301 P19320 P53708 P56199

Human

Ki: 47 IC50: 3054 Kd: 7 EC50: 37 Other: 3

Integrin alpha-1/beta-1 P05556 P56199

Human

IC50: 1

Integrin alpha-1/beta-1 [T112H] P05556 P56199

Human

Integrin alpha-10/beta-1 O75578 P05556

Human

IC50: 1

Integrin alpha-2/beta-1 P05556 P17301

Human

IC50: 47 EC50: 2

Integrin alpha-2/beta-1 [T112H] P05556 P17301

Human

IC50: 33

Integrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1 P05556 P13612 P19320

Human

IC50: 40

Integrin alpha-4/beta-1 P05556 P13612

Human

IC50: 1793 Kd: 1 EC50: 16

Integrin alpha-4/beta-1 [T112H] P05556 P13612

Human

Ki: 44 IC50: 201 Other: 3

Integrin alpha-5/beta-1 P05556 P08648

Human

IC50: 597 Kd: 4 EC50: 19

Integrin alpha-5/beta-1 [T112H] P05556 P08648

Human

IC50: 70

Integrin alpha-8/beta-1 P05556 P53708

Human

IC50: 17

Integrin alpha-V/beta-1 P05556 P06756

Human

Ki: 3 IC50: 253 Kd: 2

Integrin beta-1 P05556

Human

IC50: 1

INTEGRIN BETA-2 P05107 P05362 P11215 P20701

Human

IC50: 473 Kd: 50 EC50: 23

Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 P05107 P05362 P20701

Human

IC50: 331

Integrin alpha-L/beta-2 P05107 P20701

Human

IC50: 116 Kd: 50 EC50: 11

Integrin alpha-M/beta-2 P05107 P11215

Human

IC50: 6 EC50: 12

Integrin beta-2/Intercellular adhesion molecule 1 P05107 P05362

Human

IC50: 20

INTEGRIN BETA-3 D3ZAC0 O54890 P05106 P06756 P08514 P17301 P18084 P26006 P43406 Q8R2H2 Q9QUM0

Ki: 431 IC50: 4775 Kd: 120 EC50: 46

Integrin alpha-2/beta-3 P05106 P17301

Human

IC50: 31

Integrin alpha-3/beta-3 P05106 P26006

Human

IC50: 47

Integrin alpha-IIb/beta-3 P05106 P08514

Human

Ki: 203 IC50: 2638 Kd: 115 EC50: 21

Integrin alpha-IIb/beta-3 O54890 Q9QUM0

Mouse

IC50: 1

Integrin alpha-V/beta-3 P05106 P06756

Human

Ki: 228 IC50: 2042 Kd: 5 EC50: 23

Integrin alpha-V/beta-3 O54890 P43406

Mouse

IC50: 1

Integrin alpha-V/beta-3/beta-5 P05106 P06756 P18084

Human

IC50: 8

Integrin beta-3 O54890

Mouse

IC50: 1

Integrin beta-3 Q8R2H2

Rat

IC50: 6 EC50: 1

Integrin beta-3/subunit alpha 2b D3ZAC0 Q8R2H2

Rat

EC50: 1

INTEGRIN BETA-5 P05106 P06756 P18084

Human

Ki: 5 IC50: 585 Kd: 2 EC50: 14

Integrin alpha-V/beta-3/beta-5 P05106 P06756 P18084

Human

IC50: 8

Integrin alpha-V/beta-5 P06756 P18084

Human

Ki: 5 IC50: 577 Kd: 2 EC50: 14

INTEGRIN BETA-6 P06756 P08648 P18564 P26012

Human

Ki: 21 IC50: 1747 Kd: 2 EC50: 16

Integrin alpha-5/beta-6 P08648 P18564

Human

IC50: 175

Integrin alpha-5/beta-6/beta-8 P08648 P18564 P26012

Human

IC50: 1

Integrin alpha-V/beta-6 P06756 P18564

Human

Ki: 21 IC50: 1571 Kd: 2 EC50: 16

INTEGRIN BETA-7 P13612 P26010 P26011 Q00651 Q13477 Q61826

IC50: 703 EC50: 1

Integrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1 P13612 P26010 Q61826

Human

IC50: 153

Integrin alpha-4/beta-7 P13612 P26010

Human

IC50: 506 EC50: 1

Integrin alpha-4/beta-7 P26011 Q00651

Mouse

IC50: 4

Integrin beta-7 P26010

Human

IC50: 2

Mucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7 P13612 P26010 Q13477

Human

IC50: 38

INTEGRIN BETA-8 P06756 P08648 P18564 P26012

Human

IC50: 282 Kd: 2

Integrin alpha-5/beta-6/beta-8 P08648 P18564 P26012

Human

IC50: 1

Integrin alpha-5/beta-8 P08648 P26012

Human

IC50: 3

Integrin alpha-V/beta-8 P06756 P26012

Human

IC50: 273 Kd: 2

Integrin beta-8 P26012

Human

IC50: 5

Integrin beta-3/subunit alpha 2b D3ZAC0 Q8R2H2

Rat

EC50: 1

INTERCELLULAR ADHESION MOLECULE 1 P05107 P05362 P20701

Human

IC50: 666 EC50: 2

Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 P05107 P05362 P20701

Human

IC50: 331

Integrin alpha-L/Intercellular adhesion molecule 1 P05362 P20701

Human

IC50: 101 EC50: 2

Integrin beta-2/Intercellular adhesion molecule 1 P05107 P05362

Human

IC50: 20

Intercellular adhesion molecule 1 P05362

Human

IC50: 214

Interferon alpha-1/13/Tyrosine-protein kinase JAK1/Non-receptor tyrosine-protein kinase TYK2 P01562 P23458 P29597

Human

IC50: 37

Interferon alpha/beta receptor 1 P17181

Human

Kd: 1

Interferon gamma P01579

Human

Kd: 3

Interferon gamma receptor 1 P15260

Human

IC50: 232

Interferon regulatory factor 3 Q14653

Human

EC50: 47

Interferon-induced, double-stranded RNA-activated protein kinase P19525

Human

Ki: 13 IC50: 117 Kd: 131 EC50: 2

Interferon-inducible protein AIM2 Q91VJ1

Mouse

IC50: 3

Interleukin enhancer-binding factor 3 Q12906

Human

Kd: 2

Interleukin-1 alpha P16598

Rat

Ki: 1

INTERLEUKIN-1 BETA P01584 P10749

Ki: 1 IC50: 449 ITC: 9

Interleukin-1 beta P10749

Mouse

IC50: 1

hIL-1beta P01584

Human

Ki: 1 IC50: 448 ITC: 9

INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN P18510 P25085

Ki: 16 IC50: 82 EC50: 447

Interleukin-1 receptor antagonist protein P18510

Human

Ki: 16 IC50: 63 EC50: 447

Interleukin-1 receptor antagonist protein P25085

Mouse

IC50: 19

Interleukin-1 receptor type 1 P14778

Human

IC50: 3 Kd: 1

INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 P51617

Human

Ki: 24 IC50: 687 Kd: 95

Interleukin-1 receptor-associated kinase 1 P51617

Human

Ki: 24 IC50: 332 Kd: 95

Interleukin-1 receptor-associated kinase 1 [184-712] P51617

Human

IC50: 1

Interleukin-1 receptor-associated kinase 1 [194-712] P51617

Human

IC50: 354

Interleukin-1 receptor-associated kinase 3 Q9Y616

Human

IC50: 26 Kd: 135

INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 A0A8I3Q059 D4A7K4 Q8R4K2 Q9NWZ3

Ki: 800 IC50: 12421 Kd: 81 EC50: 160

Interleukin 1 receptor associated kinase 4 A0A8I3Q059

Dog

IC50: 2

Interleukin-1 receptor-associated kinase 4 Q9NWZ3

Human

Ki: 800 IC50: 12298 Kd: 81 EC50: 158

Interleukin-1 receptor-associated kinase 4 Q8R4K2

Mouse

IC50: 1

Interleukin-1 receptor-associated kinase 4 D4A7K4

Rat

EC50: 2

Interleukin-1 receptor-associated kinase 4 [154-460] Q9NWZ3

Human

IC50: 120

Interleukin-1 receptor-associated kinase-like 2 O43187

Human

Kd: 1

Interleukin-10 P22301

Human

EC50: 7

Interleukin-13 P35225

Human

IC50: 230

INTERLEUKIN-15 P40933 P48346

IC50: 75 Kd: 20

Interleukin-15 P48346

Mouse

IC50: 50

Interleukin-15 P40933

Human

IC50: 25 Kd: 20

Interleukin-17 receptor A/ Q16552 Q96F46

Human

IC50: 230

Interleukin-17 receptor E Q8NFR9

Human

IC50: 78

INTERLEUKIN-17A Q16552 Q96F46

Human

IC50: 327 Kd: 19

Interleukin-17 receptor A/ Q16552 Q96F46

Human

IC50: 230

Interleukin-17A Q16552

Human

IC50: 97 Kd: 19

Interleukin-17F Q96PD4

Human

IC50: 162

INTERLEUKIN-18 P97636 Q14116

Ki: 1 EC50: 1

Interleukin-18 P97636

Rat

Ki: 1

Interleukin-18 Q14116

Human

EC50: 1

INTERLEUKIN-2 P04351 P60568

Ki: 1 IC50: 258 Kd: 41 EC50: 329

Interleukin-2 P60568

Human

Ki: 1 IC50: 254 Kd: 41 EC50: 329

Interleukin-2 P04351

Mouse

IC50: 4

INTERLEUKIN-2 RECEPTOR SUBUNIT ALPHA P01589 P01590

IC50: 41 EC50: 2

Interleukin-2 receptor subunit alpha P01589

Human

IC50: 2

Interleukin-2 receptor subunit alpha P01590

Mouse

IC50: 39 EC50: 2

Interleukin-21 Q9HBE4

Human

IC50: 35

Interleukin-22 Q9GZX6

Human

IC50: 4

Interleukin-22 receptor subunit alpha-2 Q969J5

Human

IC50: 9

Interleukin-23 receptor Q5VWK5

Human

IC50: 2 Kd: 1 Koff: 1

Epidermal growth factor receptor/Interleukin-3 P00533 P08700

Human

IC50: 12

Interleukin-33 O95760

Human

IC50: 2

Interleukin-36 gamma Q9NZH8

Human

Kd: 1

Interleukin-4 P05112

Human

IC50: 230 Kd: 1 EC50: 1

INTERLEUKIN-5 P04401 P05113

IC50: 207

Interleukin-5 P04401

Mouse

IC50: 204

Interleukin-5 P05113

Human

IC50: 3

Interleukin-5 receptor subunit alpha P21183

Mouse

IC50: 27

Interleukin-6 P05231

Human

IC50: 48 EC50: 105

Interleukin-6 receptor subunit alpha P22273

Rat

Ki: 2

Interleukin-6 receptor subunit beta P40189

Human

IC50: 15 Kd: 3

Interleukin-8 P10145

Human

Ki: 14 IC50: 71 Kd: 1

INTERSTITIAL COLLAGENASE P03956 P08253 P14780 P22894 P45452

Human

Ki: 1287 IC50: 3168 Kd: 2 EC50: 18

72 kDa type IV collagenase/Collagenase 3/Interstitial collagenase/Matrix metalloproteinase-9/Neutrophil collagenase P03956 P08253 P14780 P22894 P45452

Human

Ki: 68 IC50: 6

Interstitial collagenase P03956

Human

Ki: 1219 IC50: 3154 Kd: 2 EC50: 18

Interstitial collagenase [100-268] P03956

Human

IC50: 8

INTESTINAL-TYPE ALKALINE PHOSPHATASE P09923 P19111 P24822

Ki: 44 IC50: 557 EC50: 322

Intestinal-type alkaline phosphatase P19111

Bovine

Ki: 43 IC50: 120

Intestinal-type alkaline phosphatase P24822

Mouse

Ki: 1 IC50: 55

Intestinal-type alkaline phosphatase P09923

Human

IC50: 382 EC50: 322

Intestinal-type alkaline phosphatase 1 P15693

Rat

IC50: 264 EC50: 97

Intracellular chorismate mutase P9WIC1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 2

INVOLVED IN NUCLEOTIDE METABOLISM A3RLP8 O72346 P04407 P06479 P09250 P13159 Q0H0G9 Q6L709 Q6QCL9 Q9PPP5 Q9QNF7

Ki: 9 IC50: 470 EC50: 303

Thymidine kinase O72346

HHV-1

Ki: 1 IC50: 29

Thymidine kinase P04407

HHV-2

Ki: 1 IC50: 29

Thymidine kinase Q9QNF7

HHV-1

Ki: 1 IC50: 61

Thymidine kinase P09250

HHV-3

IC50: 55

Thymidine kinase Q6L709

HHV-2

IC50: 85

Thymidine kinase Q0H0G9

Staphylococcus aureus

Ki: 2

Thymidine kinase Q9PPP5

Ureaplasma parvum

IC50: 10

Thymidine kinase P13159

FeHV-1

IC50: 4

Thymidine kinase Q9QNF7

HHV-1

Ki: 2 IC50: 49

Thymidine kinase A3RLP8

CeHV-1

IC50: 17

Thymidine kinase P06479

HHV-1

Ki: 2 IC50: 127 EC50: 97

Thymidine kinase Q6QCL9

HHV-3

IC50: 4 EC50: 206

Inward rectifier potassium channel 13 O60928

Human

IC50: 5

INWARD RECTIFIER POTASSIUM CHANNEL 2 P35561 P63252

IC50: 45

Inward rectifier potassium channel 2 P35561

Mouse

IC50: 23

Inward rectifier potassium channel 2 P63252

Human

IC50: 22

Inward rectifier potassium channel 4 P48050

Human

IC50: 6

Iodotyrosine deiodinase [1-228] F4KU78

Haliscomenobacter hydrossis

Kd: 5

Iodotyrosine deiodinase 1 [1-1,32-289] Q6PHW0

Human

Kd: 2

Ion channel NompC Q7T1G6

Zebrafish

EC50: 271

Ionotropic glutamate receptor subunit Delta2 B9V8R6

African clawed frog

Ki: 25

Iron-starvation protein PigA O69002

Pseudomonas aeruginosa

Kd: 59

Islet amyloid polypeptide P10997

Human

IC50: 19

iso-1-cytochrome c (Cc) A6ZQ07

Saccharomyces cerevisiae

ITC: 13

Isochorismate synthase EntC P0AEJ2

Escherichia coli (strain K12)

Ki: 13

ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC O75874 P48735

Human

Ki: 140 IC50: 13436 Kd: 51 EC50: 7

Isocitrate dehydrogenase [NADP] cytoplasmic O75874

Human

Ki: 140 IC50: 3067 Kd: 51 EC50: 7

Isocitrate dehydrogenase [NADP] cytoplasmic [1-390,401-414,R132C] O75874

Human

IC50: 21

Isocitrate dehydrogenase [NADP] cytoplasmic [R132C] O75874

Human

IC50: 2244

Isocitrate dehydrogenase [NADP] cytoplasmic [R132C] O75874

Human

IC50: 98

Isocitrate dehydrogenase [NADP] cytoplasmic [R132G] O75874

Human

IC50: 3

Isocitrate dehydrogenase [NADP] cytoplasmic [R132H] O75874

Human

IC50: 7649

Isocitrate dehydrogenase [NADP] cytoplasmic [R132H] O75874

Human

IC50: 346

Isocitrate dehydrogenase [NADP] cytoplasmic [R132L] O75874

Human

IC50: 1

Isocitrate dehydrogenase [NADP] cytoplasmic [R132S] O75874

Human

IC50: 1

Isocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial O75874 P48735

Human

IC50: 6

ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL O75874 P48735

Human

IC50: 1554

Isocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial O75874 P48735

Human

IC50: 6

Isocitrate dehydrogenase [NADP], mitochondrial P48735

Human

IC50: 367

Isocitrate dehydrogenase [NADP], mitochondrial [40-452,R172K] P48735

Human

IC50: 18

Isocitrate dehydrogenase [NADP], mitochondrial [R140Q] P48735

Human

IC50: 1117

Isocitrate dehydrogenase [NADP], mitochondrial [R140Q] P48735

Human

IC50: 23

Isocitrate dehydrogenase [NADP], mitochondrial [R172K] P48735

Human

IC50: 21

Isocitrate dehydrogenase [NADP], mitochondrial [R172S] P48735

Human

IC50: 2

ISOCITRATE LYASE P0CT06 P9WKK7 Q9P8Q7

IC50: 225

Isocitrate lyase P9WKK7

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 34

Isocitrate lyase Q9P8Q7

Yeast

IC50: 170

Isocitrate lyase P0CT06

Rice blast fungus

IC50: 21

ISOLEUCINE--TRNA LIGASE P00956 P41972 Q38A55

Ki: 30 IC50: 62

Isoleucine--tRNA ligase P00956

Escherichia coli (strain K12)

Ki: 30 IC50: 24

Isoleucine--tRNA ligase Q38A55

Trypanosoma brucei brucei (strain 927/4 GUTat10.1)

IC50: 1

Isoleucine--tRNA ligase P41972

Staphylococcus aureus

IC50: 37

Isoleucine--tRNA ligase, cytoplasmic P41252

Human

IC50: 82

Isoleucyl-tRNA synthetase O35880

Rat

IC50: 27

Isopentenyl-diphosphate Delta-isomerase Q46822

Escherichia coli (strain K12)

Ki: 3 IC50: 5

Isopentenyl-diphosphate Delta-isomerase 1 O35760

Rat

IC50: 1

Isoprenyl transferase Q97SR4

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

IC50: 32

IspB protein B7LHQ0

Escherichia coli (Enterobacteria)

IC50: 2

Curated by BindingDB

Curated by ChEMBL