60 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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(+)-and (-)-Phenazocine enantiomers: Evaluation of their dual opioid agonist/s
University of Catania
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT
University of Catania
Evaluation of N-substituent structural variations in opioid receptor profile of LP1.
University of Catania
Multitarget opioid ligands in pain relief: New players in an old game.
University of Catania
Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.
University of Catania
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands.
University of Catania
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction.
University of Catania
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT(7) and 5-HT(1A) receptor ligands.
University of Catania
Studies on molecular properties prediction and histamine H3 receptor affinities of novel ligands with uracil-based motifs.
University of Catania
High affinity ligands and potent antagonists for thea1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives.
University of Catania
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.
University of Catania
Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity.
University of Catania
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands fora1-adrenoceptor subtypes.
University of Catania
New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes.
University of Catania
Synthesis of (+)-cis-N-(4-isothiocyanatobenzyl)-N-normetazocine, an isothiocyanate derivative of N-benzylnormetazocine as acylant agent for the sigma(1) receptor.
University of Catania
Nonpeptide analogues of dynorphin A(1-8): design, synthesis, and pharmacological evaluation of kappa-selective agonists.
University of Catania
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties.
University of Catania
Non-peptide ligands for opioid receptors. Design of kappa-specific agonists.
University of Catania
Novel inhibitors of nitric oxide synthase with antioxidant properties.
University of Catania
Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for thea1-adrenoceptors.
University of Catania
Novel potent and selectives ligands: evaluation of their agonist and antagonist properties.
University of Catania
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells.
University of Catania
Synthesis and resolution of cis-(+/-)-methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(+/-)-PPCC)]: new sigma receptor ligands with neuroprotective effect.
University of Catania
Inhibition of iNOS and COX-2 in human whole blood ex vivo and monocyte-macrophage J774 cells by a new group of aminothiopyrimidone derivatives.
University of Catania
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review.
University of Catania
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation.
University of Catania
6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid mimics active conformation of tyrosine in opioid peptides.
University of Catania
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. An update from 2017 to early 2022.
University of Catania
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent
University of Catania
Kappa-opioid receptor model in a phospholipid bilayer: molecular dynamics simulation.
University of Catania
New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation.
University of Catania
Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation.
University of Catania
Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells.
University of Catania
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation.
University of Catania
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application.
University of Catania
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain.
University of Catania
Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.
University of Catania
Progress in the development of more effective and safer analgesics for pain management.
University of Catania
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.
University of Catania
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.
University of Catania
(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist.
University of Catania
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT
University of Catania
Resveratrol-Related Polymethoxystilbene Glycosides: Synthesis, Antiproliferative Activity, and Glycosidase Inhibition.
University of Catania
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes.
University of Catania
A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors.
University of Catania
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.
University of Catania
Structure-Activity Relationships and Therapeutic Potentials of 5-HT
University of Catania
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review.
University of Catania
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors.
University of Catania
Serendipitous discovery of potent human head and neck squamous cell carcinoma anti-cancer molecules: A fortunate failure of a rational molecular design.
University of Catania
Development of novel LP1-based analogues with enhanced delta opioid receptor profile.
University of Catania
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties.
University of Catania
Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.
University of Catania
Primary amines and derivitves thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
Arena Pharmaceuticals