Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50046993
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142699(CHEMBL3759831)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at rat mu opioid receptor transfected in C6 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135806(MCL-144 | di[17-cyclobutylmethyl-(1R,9R,10R)-17-az...)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135806(MCL-144 | di[17-cyclobutylmethyl-(1R,9R,10R)-17-az...)
Affinity DataEC50:  1.30nMAssay Description:Partial agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataEC50:  32nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced twitchesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142697(CHEMBL3759294)
Affinity DataEC50:  22nMAssay Description:Agonist activity at rat delta opioid receptor transfected in C6 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142691(CHEMBL3758348)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142694(CHEMBL3759660)
Affinity DataEC50:  73nMAssay Description:Partial agonist activity at mu opioid receptor (unknown origin) expressed in CHO cell membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142699(CHEMBL3759831)
Affinity DataEC50:  22nMAssay Description:Agonist activity at rat delta opioid receptor transfected in C6 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142697(CHEMBL3759294)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at rat mu opioid receptor transfected in C6 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142622(CHEMBL3758292)
Affinity DataEC50:  0.0813nMAssay Description:Agonist activity at human delta-opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142703(CHEMBL3759541)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142690(CHEMBL3759489)
Affinity DataEC50:  45nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) assessed as [35S]GTPgammaS binding by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142620(CHEMBL3758712)
Affinity DataEC50:  3nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142696(CHEMBL3758259)
Affinity DataEC50:  36nMAssay Description:Partial agonist activity at delta opioid receptor (unknown origin) assessed as inhibition of adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142690(CHEMBL3759489)
Affinity DataEC50:  0.870nMAssay Description:Partial agonist activity at delta opioid receptor (unknown origin) assessed as [35S]GTPgammaS binding by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135797(di[17-cyclobutylmethyl-(1R,9R,10R)-17-azatetracycl...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142622(CHEMBL3758292)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142704(CHEMBL3758563)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 1nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced twitchesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataIC50: 1.40nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142704(CHEMBL3758563)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO-induced [35S]-GTP-gammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human delta opioid receptor in CD1 mouse assessed as electrically induced twitchesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142703(CHEMBL3759541)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO-induced [35S]-GTP-gammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataIC50: 37nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142702(CHEMBL3758231)
Affinity DataIC50: 67nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataIC50: 1.25E+3nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142700(CHEMBL326684)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50299217((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.0160nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142622(CHEMBL3758292)
Affinity DataKi:  0.0210nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.0310nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142620(CHEMBL3758712)
Affinity DataKi:  0.0420nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135806(MCL-144 | di[17-cyclobutylmethyl-(1R,9R,10R)-17-az...)
Affinity DataKi:  0.0490nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142694(CHEMBL3759660)
Affinity DataKi:  0.0490nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135808(CHEMBL301160 | (-)-3-Hydroxy-N-cyclobutylmethylmor...)
Affinity DataKi:  0.0730nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135797(di[17-cyclobutylmethyl-(1R,9R,10R)-17-azatetracycl...)
Affinity DataKi:  0.0780nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135806(MCL-144 | di[17-cyclobutylmethyl-(1R,9R,10R)-17-az...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135808(CHEMBL301160 | (-)-3-Hydroxy-N-cyclobutylmethylmor...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataKi:  0.143nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.151nMAssay Description:Displacement of [3H]DPN from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.160nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142620(CHEMBL3758712)
Affinity DataKi:  0.160nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142693(CHEMBL3759238)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]DPDPE from mu opioid receptor in albino Sprague-Dawley rat after 90 mins by liquid scintillationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135797(di[17-cyclobutylmethyl-(1R,9R,10R)-17-azatetracycl...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142705(CHEMBL3758257)
Affinity DataKi:  0.259nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142695(CHEMBL3759663)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor transfected in C6 cells by liquid scintillation counting assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142693(CHEMBL3759238)
Affinity DataKi:  0.380nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142619(CHEMBL3759383)
Affinity DataKi:  0.440nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in albino Sprague-Dawley rat after 90 mins by liquid scintillationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 85 total ) | Next | Last >>
Jump to: