Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 50009445
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  76nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50518035(CHEMBL4452384 | US10751335, Example 16)
Affinity DataEC50:  501nMAssay Description:Inhibition of human mu-opioid receptor assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528963(CHEMBL4530626)
Affinity DataEC50:  203nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50518036(CHEMBL4467777 | US11484525, Compound BD-122LS-PZM2...)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM83396(ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenyleth...)
Affinity DataEC50:  8.30E+3nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in human UO5S cells assessed as increase in beta arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM83396(ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenyleth...)
Affinity DataEC50:  54nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in human UO5S cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50399882(CHEMBL2180638)
Affinity DataEC50:  37nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50399881(CHEMBL2180639)
Affinity DataEC50:  5nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528964(CHEMBL4464797)
Affinity DataEC50:  0.190nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50491417(22-THIOCYANATOSALVINORIN A)
Affinity DataEC50:  0.0770nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50491417(22-THIOCYANATOSALVINORIN A)
Affinity DataKd:  0.590nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50518036(CHEMBL4467777 | US11484525, Compound BD-122LS-PZM2...)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528966(CHEMBL4521879)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528967(CHEMBL4439415)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528968(CHEMBL4577301)
Affinity DataEC50:  1.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  53nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  53nMAssay Description:Agonist activity at mu opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataEC50:  230nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  5.20nMAssay Description:Inhibition of p38 phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  0.550nMAssay Description:Inhibition of ERK1 phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528970(CHEMBL4522339)
Affinity DataEC50:  1.60E+4nMAssay Description:Partial agonist activity at mu opioid receptor (unknown origin) expressed in CHO cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  107nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as effect on ERK1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  1.01E+4nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50518022(CHEMBL4458783)
Affinity DataEC50:  4.13E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM65817(KSC-5-240 | ML138 | KUC103893N | cid_44601470 | 2-...)
Affinity DataEC50:  1.40E+5nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitment relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528971(CHEMBL4582676)
Affinity DataEC50:  7.94E+4nMAssay Description:Inhibition of full length delta opioid receptor (unknown origin) assessed as increase in beta arrestin 1 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50459352(CHEMBL4217435 | US10751335, Example 15)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of human mu-opioid receptor assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50459352(CHEMBL4217435 | US10751335, Example 15)
Affinity DataEC50:  501nMAssay Description:Inhibition of human mu-opioid receptor assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50459364(CHEMBL4210060 | US10751335, Example 1)
Affinity DataEC50:  91nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50459363(CHEMBL4202958 | US10751335, Example 4)
Affinity DataEC50:  355nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528972(CHEMBL4577586)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528973(CHEMBL4581231)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528974(CHEMBL4462475)
Affinity DataEC50:  456nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528975(CHEMBL4456635)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528975(CHEMBL4456635)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528976(CHEMBL4474914)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528977(CHEMBL579408 | GNF-Pf-4596)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataEC50:  230nMAssay Description:Agonist activity at mu opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  107nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as effect on ERK2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50518035(CHEMBL4452384 | US10751335, Example 16)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of human mu-opioid receptor assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528972(CHEMBL4577586)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528974(CHEMBL4462475)
Affinity DataEC50:  456nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataEC50:  940nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 109 total ) | Next | Last >>
Jump to: