Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50002441
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataKi:  0.153nMAssay Description:Displacement of [3H]lysergic acid from 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat recombinant 5-HT7 receptor expressed in HEK293 cell membranes incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458532(CHEMBL4216782)
Affinity DataKi:  0.470nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50004891(CHEMBL2164327)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.930nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to 5-HT2c receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human 5-HT7 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458529(CHEMBL4204059)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]5-CT from human 5-HT7b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458527(CHEMBL4218549)
Affinity DataKi:  2nMAssay Description:Binding affinity to human 5-HT7 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50116963(2a-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50329676(1-(3-methoxyphenethyl)-4-(2-methoxyphenyl)piperazi...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A in rat hippocampal membranes incubated for 20 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human 5-HT7 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458525(CHEMBL4211987)
Affinity DataKi:  4nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458530(CHEMBL4216263)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]5-CT from rat 5-HT7 receptor expressed in HEK293 cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458528(CHEMBL4208934)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]5-CT from human 5-HT7b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458531(CHEMBL4207454)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]lysergide from rat recombinant 5-HT7 receptor expressed in HEK293 cell membranes incubated for 60 mins by radioligand binding ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458529(CHEMBL4204059)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in HEK293 cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458529(CHEMBL4204059)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458528(CHEMBL4208934)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in HEK293 cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458531(CHEMBL4207454)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A in rat hippocampal membranes incubated for 20 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50329676(1-(3-methoxyphenethyl)-4-(2-methoxyphenyl)piperazi...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]lysergide from rat recombinant 5-HT7 receptor expressed in HEK293 cell membranes incubated for 60 mins by radioligand binding ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458524(CHEMBL4204595)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50098550(SB-258719 | CHEMBL12264 | 3,N-Dimethyl-N-[1-methyl...)
Affinity DataKi:  32nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458529(CHEMBL4204059)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50240359(1-(5-(4-phenylpiperazin-1-yl)pentyl)benzo[cd]indol...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-5-CT from from 5-HT7 receptor in rat hypothalamus membranes by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458528(CHEMBL4208934)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458528(CHEMBL4208934)
Affinity DataKi:  466nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50020221((-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen...)
Affinity DataKi:  466nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458529(CHEMBL4204059)
Affinity DataKi:  637nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in HEK293 cell membranes incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458528(CHEMBL4208934)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in HEK293 cell membranes incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed