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47 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening.EBI
University of Naples Federico Ii
Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv."Cascade").EBI
University of Naples Federico Ii
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.EBI
University of Naples Federico II
Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges.EBI
University of Naples Federico II
Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3ß inhibitors.EBI
University of Naples Federico II
Characterization of a selective CaMKII peptide inhibitor.EBI
University of Naples Federico Ii
New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide.EBI
University of Naples Federico Ii
Novel and selective alpha(v)beta3 receptor peptide antagonist: design, synthesis, and biological behavior.EBI
University of Naples Federico Ii
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor¿.EBI
University of Naples Federico II
Kallikrein protease activated receptor (PAR) axis: an attractive target for drug development.EBI
University of Naples Federico II
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer.EBI
University of Naples Federico II
Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening.EBI
University of Naples Federico II
STAT-3 inhibitory bisabolanes from Carthamus glaucus.EBI
University of Naples Federico II
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein.EBI
University of Naples Federico II
Petrosaspongiolides M-R: new potent and selective phospholipase A2 inhibitors from the New Caledonian marine sponge Petrosaspongia nigra.EBI
University of Naples Federico II
2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching.EBI
University of Naples Federico II
Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.EBI
University of Naples Federico Ii
Modeling of kappa-opioid receptor/agonists interactions using pharmacophore-based and docking simulations.EBI
University of Naples Federico II
A comparative molecular field analysis model for 6-arylpyrrolo[2,1-d] [1,5]benzothiazepines binding selectively to the mitochondrial benzodiazepine receptor.EBI
University of Naples Federico II
Synthesis and antihistaminic activity of some thiazolidin-4-ones.EBI
University of Naples Federico II
Beta-casomorphins: substitution of phenylalanine with beta-homo phenylalanine increases the mu-type opioid receptor affinity.EBI
University of Naples Federico II
New potent 5-HT(2A) receptor ligands containing an N'-cyanopicolinamidine nucleus: Synthesis and in vitro pharmacological evaluation.EBI
University of Naples Federico II
Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: a first round of lead optimization.EBI
University of Naples Federico II
Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents.EBI
University of Naples Federico II
New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: synthesis and in vitro pharmacological evaluation.EBI
University of Naples Federico II
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.EBI
University of Naples Federico II
Phytochemical Characterization and TRPA1/TRPM8 Modulation Profile of the Cannabigerol-Rich EBI
University of Naples Federico Ii
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.EBI
University of Naples Federico Ii
Easy access to α-ketoamides as SARS-CoV-2 and MERS MEBI
University of Naples Federico Ii
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand.EBI
University of Naples Federico II
Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their"receptor desmodynamic processes".EBI
University of Naples Federico Ii
CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.EBI
University of Naples Federico II
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.EBI
University of Naples Federico II
Cannabitwinol, a Dimeric Phytocannabinoid from Hemp, EBI
University of Naples Federico Ii
Structure and Configuration of Phosphoeleganin, a Protein Tyrosine Phosphatase 1B Inhibitor from the Mediterranean Ascidian Sidnyum elegans.EBI
University of Naples Federico Ii
Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology.EBI
University of Naples Federico II
Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach.EBI
University of Naples Federico Ii
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases.EBI
University of Naples Federico Ii
Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines.EBI
University of Naples Federico Ii
Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.EBI
University of Naples Federico II
A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge.EBI
University of Naples Federico Ii
Iodine-mediated cyclization of cannabigerol (CBG) expands the cannabinoid biological and chemical space.EBI
University of Naples Federico II
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors.EBI
University of Naples Federico II
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.EBI
University of Naples Federico II
Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells.EBI
University of Naples Federico II
N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer ofα-Glucosidase Activity for the Treatment of Pompe Disease.EBI
University of Naples Federico II
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.EBI
University of Naples Federico II