Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50000257
TargetSucrase-isomaltase(Mouse)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild type C57BL/6 mouse small intestinal sucrase/isomaltase using sucrose as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of rat liver lysosomal alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of recombinant human GAA by UV-visible spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed
TargetLysosomal acid/Non-lysosomal glucosylceramidase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of GBA1/GBA2 derived from human HL60 cells using 4-MU-Glc as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant human GBA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed
TargetSucrase-isomaltase(Mouse)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50243651(CHEMBL4061367)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of wild type C57BL/6 mouse small intestinal sucrase/isomaltase using sucrose as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed
TargetBeta-galactosidase(Mouse)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50243651(CHEMBL4061367)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of wild type C57BL/6 mouse small intestinal lactase using lactose as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2019
Entry Details Article
PubMed