Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50033496
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346374(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...)
Affinity DataKi:  0.000178nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi:  0.293nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(S-(-)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthale...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi:  0.850nMAssay Description:Binding affinity to 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346377(4-[2-[4-(naphthalen)piperazin-1-yl]ethoxy]-4-aza-t...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346374(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...)
Affinity DataKi:  5.29nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  5.85nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346376(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...)
Affinity DataKi:  7.79nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346380(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)be...)
Affinity DataKi:  85.4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi:  91.8nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346377(4-[2-[4-(naphthalen)piperazin-1-yl]ethoxy]-4-aza-t...)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346376(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346381(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  172nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi:  263nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346380(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)be...)
Affinity DataKi:  721nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346379(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethoxy)ben...)
Affinity DataKi:  1.32E+3nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346381(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346379(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethoxy)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346377(4-[2-[4-(naphthalen)piperazin-1-yl]ethoxy]-4-aza-t...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346374(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346381(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346377(4-[2-[4-(naphthalen)piperazin-1-yl]ethoxy]-4-aza-t...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346380(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)be...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346376(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346374(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346376(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346374(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346381(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346380(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)be...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346379(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethoxy)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346376(3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346379(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethoxy)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed