BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.0M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 685K Compounds and 4.6K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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7 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.EBI
University of Naples Federico II
Optimization of BAX trigger site activator BTSA1 with improved antitumor potency and in vitro ADMET properties.EBI
Shenyang Pharmaceutical University
Pharmacological Targeting of Executioner Proteins: Controlling Life and Death.EBI
University of Toronto
Further lead optimization on Bax activators: Design, synthesis and pharmacological evaluation of 2-fluoro-fluorene derivatives for the treatment of breast cancer.EBI
University of Texas Medical Branch (Utmb)
HDAC-Bax Multiple Ligands Enhance Bax-Dependent Apoptosis in HeLa Cells.EBI
Shandong University
Quinolone hybrids and their anti-cancer activities: An overview.EBI
Qilu University of Technology (Shandong Academy of Sciences)
Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer.EBI
University of Texas Medical Branch