Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50018637
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50610525(CHEMBL4578793)
Affinity DataKd:  255nMAssay Description:Binding affinity to recombinant human BAX assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM398051(US10322118, Entry 9)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to BAX (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50610528(CHEMBL5289201)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to recombinant human BAX (1 to 92 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant incubated for...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM196140(US9211296, Table 7, Compd: 13)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to recombinant human BAX (1 to 92 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant incubated for...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50610526(CHEMBL5282360)
Affinity DataIC50: 250nMAssay Description:Binding affinity to recombinant human full length GST-tagged BAX expressed in Escherichia coli BL21 (DE3) measured after 20 mins by fluorescence pola...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50610527(CHEMBL5266955)
Affinity DataIC50: 3.30E+3nMAssay Description:Binding affinity to recombinant human full length GST-tagged BAX expressed in Escherichia coli BL21 (DE3) measured after 20 mins by fluorescence pola...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50610529(CHEMBL5278460)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human BAX expressed in Escherichia coli BL21 (DE3) assessed as inhibition of liposome permeabilization and measured for 2 h...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50610530(CHEMBL5271207)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human BAX expressed in Escherichia coli BL21 (DE3) assessed as inhibition of liposome permeabilization and measured for 2 h...More data for this Ligand-Target Pair
In DepthDetails
PubMed