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27 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRa from Drugbank database.EBI
Xiamen University
Binding characterization, synthesis and biological evaluation of RXRa antagonists targeting the coactivator binding site.EBI
Xiamen University
Synthesis and SAR study of modulators inhibiting tRXRa-dependent AKT activation.EBI
Xiamen University
Cytosporone B is an agonist for nuclear orphan receptor Nur77.EBI
Xiamen University
Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2.EBI
Xiamen University
Discovery of 5-(Pyrimidin-2-ylamino)-1EBI
Xiamen University
Dihydrotrichodimerol Purified from the Marine Fungus EBI
Xiamen University
A Molecular Toolbox of Positron Emission Tomography Tracers for General Anesthesia Mechanism Research.EBI
Xiamen University
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.EBI
Xiamen University
Inhibitory effects of phloridzin dihydrate on the activity of mushroom (Agaricus bisporus) tyrosinase.EBI
Xiamen University
Discovery of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as novel anti-cancer agents targeting Nur77.EBI
Xiamen University
Design, synthesis, and biological evaluation of novel sulindac derivatives as partial agonists of PPARγ with potential anti-diabetic efficacy.EBI
Xiamen University
Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway.EBI
Xiamen University
Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma.EBI
Xiamen University
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.EBI
Xiamen University
Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.EBI
Xiamen University
Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors.EBI
Xiamen University
Structure-Activity Relationship Study Enables the Discovery of a Novel EBI
Xiamen University
Design, synthesis and biological evaluation of tetrazole-containing RXRα ligands as anticancer agents.EBI
Xiamen University
SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway.EBI
Xiamen University
Cytotoxic Components from Hypericum elodeoides Targeting RXRα and Inducing HeLa Cell Apoptosis through Caspase-8 Activation and PARP Cleavage.EBI
Xiamen University
In Silico Discovery of JMJD6 Inhibitors for Cancer Treatment.EBI
Xiamen University
Identification of a New RXRα Antagonist Targeting the Coregulator-Binding Site.EBI
Xiamen University
Synthesis and antityrosinase activities of alkyl 3,4-dihydroxybenzoates.EBI
Xiamen University
Substituted pyrazolopyrimidines useful as kinases inhibitorsBDB
Teligene
Ethynyl derivativesBDB
Hoffmann-La Roche
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin.BDB
Philipps University Marburg