32 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Design and synthesis of new piperidone grafted acetylcholinesterase inhibitors.
University of Nebraska Medical Center
Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.
University of Nebraska Medical Center
Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.
University of Nebraska Medical Center
Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth.
University of Nebraska Medical Center
Radiolabeled cyclosaligenyl monophosphates of 5-iodo-2'-deoxyuridine, 5-iodo-3'-fluoro-2',3'-dideoxyuridine, and 3'-fluorothymidine for molecular radiotherapy of cancer: synthesis and biological evaluation.
University of Nebraska Medical Center
Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides.
University of Nebraska Medical Center
Structure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1.
University of Nebraska Medical Center
The comparative antimalarial properties of weak base and neutral synthetic ozonides.
University of Nebraska Medical Center
Radiolabeled 5-iodo-3'-O-(17beta-succinyl-5alpha-androstan-3-one)-2'-deoxyuridine and its 5'-monophosphate for imaging and therapy of androgen receptor-positive cancers: synthesis and biological evaluation.
University of Nebraska Medical Center
Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model.
University of Nebraska Medical Center
Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability.
University of Nebraska Medical Center
From dopamine 4 to sigma 1: Synthesis, SAR and biological characterization of a piperidine scaffold of σ1 modulators.
University of Nebraska Medical Center
Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability.
University of Nebraska Medical Center
Synthesis and Biological Characterization of a Series of 2-Sulfonamidebenzamides as Allosteric Modulators of MrgX1.
University of Nebraska Medical Center
Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists.
University of Nebraska Medical Center
Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylation.
University of Nebraska Medical Center
Structure-activity relationship studies of functionalized aromatic peptidomimetics as neurolysin activators.
University of Nebraska Medical Center
Virtual screening and biological evaluation of PPARγ antagonists as potential anti-prostate cancer agents.
University of Nebraska Medical Center
Synthesis, optimization, in vitro and in vivo study of bicyclic substituted amine as MenA inhibitor.
University of Nebraska Medical Center
Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax.
University of Nebraska Medical Center
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
University of Nebraska Medical Center
Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978).
University of Nebraska Medical Center
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators.
University of Nebraska Medical Center
Norepinephrine-Transporter-Targeted and DNA-Co-Targeted Theranostic Guanidines.
University of Nebraska Medical Center
Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases.
University of Nebraska Medical Center
Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903.
University of Nebraska Medical Center
Enhanced tumor retention of NTSR1-targeted agents by employing a hydrophilic cysteine cathepsin inhibitor.
University of Nebraska Medical Center
A new chemotype with promise against Trypanosoma cruzi.
University of Nebraska Medical Center
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics.
University of Nebraska Medical Center
Decapeptide agonists of human C5a: the relationship between conformation and neutrophil response.
University of Nebraska Medical Center