Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50007000
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350315(US10208064, Example 30)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505266(CHEMBL4548110)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505268(CHEMBL4549009)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505267(CHEMBL4563446)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505271(CHEMBL4462473)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350282(US10208064, Example 2)
Affinity DataIC50: 9nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350300(US10208064, Example 19)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505263(CHEMBL4586813)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505265(CHEMBL4465260)
Affinity DataIC50: 28nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505270(CHEMBL4447159)
Affinity DataIC50: 38nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505261(CHEMBL4456474)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204280(CHEMBL3987135 | US9573961, Example 15)
Affinity DataIC50: 57nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM290057(US9573961, Example 42)
Affinity DataIC50: 60nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505264(CHEMBL4544141)
Affinity DataIC50: 65nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204281(CHEMBL3933749)
Affinity DataIC50: 73nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)
Affinity DataIC50: 240nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM73215(VU0277590-7 | 7,13-bis[(4-nitrophenyl)methyl]-1,4,...)
Affinity DataIC50: 294nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505269(CHEMBL1470194)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM290057(US9573961, Example 42)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204281(CHEMBL3933749)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505264(CHEMBL4544141)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204280(CHEMBL3987135 | US9573961, Example 15)
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505262(CHEMBL4559408)
Affinity DataKi:  2nMAssay Description:Inhibition of ROMK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetG protein-activated inward rectifier potassium channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505262(CHEMBL4559408)
Affinity DataKi:  8.20nMAssay Description:Inhibition GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed