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Discovery of new acetylcholinesterase inhibitors with small core structures through shape-based virtual screening.

Nanjing University of Chinese Medicine

Synthesis and structure-activity relationship analysis of caffeic acid amides as selective matrix metalloproteinase inhibitors.

Nanjing University of Chinese Medicine

Structure-Based Drug Design of Novel Triaminotriazine Derivatives as Orally Bioavailable IDH2

Nanjing University of Chinese Medicine

Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries.

Nanjing University of Chinese Medicine

Discovery of pyrazolo[3,4-b]pyridine derivatives as novel and potent Mps1 inhibitors for the treatment of cancer.

Nanjing University of Chinese Medicine

Structure-based discovery of novel α-aminoketone derivatives as dual p53-MDM2/MDMX inhibitors for the treatment of cancer.

Nanjing University of Chinese Medicine

Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP).

Nanjing University of Chinese Medicine

Discovery of Novel Sesquiterpene Lactone Derivatives as Potent PKM2 Activators for the Treatment of Ulcerative Colitis.

Nanjing University of Chinese Medicine

Total synthesis, chemical modification and structure-activity relationship of bufadienolides.

Nanjing University of Chinese Medicine

Selective Estrogen Receptor Degraders (SERDs): A Promising Strategy for Estrogen Receptor Positive Endocrine-Resistant Breast Cancer.

Nanjing University of Chinese Medicine

Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia.

Nanjing University of Chinese Medicine

Design, Synthesis, and Bioevaluation of Pyrido[2,3-

Nanjing University of Chinese Medicine

Discovery of 1,6-Naphthyridin-2(1

Nanjing University of Chinese Medicine

Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010-2020).

Nanjing University of Chinese Medicine

Discovery of highly potent SARS-CoV-2 M

Nanjing University of Chinese Medicine

Discovery of non-substrate, environmentally sensitive turn-on fluorescent probes for imaging HDAC8 in tumor cells and tissue slices.

Nanjing University of Chinese Medicine

Medicinal Chemistry Strategies for the Development of Bruton's Tyrosine Kinase Inhibitors against Resistance.

Nanjing University of Chinese Medicine

Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.

Nanjing University of Chinese Medicine

The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay.

Nanjing University of Chinese Medicine

Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.

Nanjing University of Chinese Medicine

Discovery of (

Nanjing University of Chinese Medicine

Dynamics-Based Discovery of Novel, Potent Benzoic Acid Derivatives as Orally Bioavailable Selective Estrogen Receptor Degraders for ERα+ Breast Cancer.

Nanjing University of Chinese Medicine

Discovery of a Potent and Selective FLT3 Inhibitor (

Nanjing University of Chinese Medicine

Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening.

Nanjing University of Chinese Medicine

Pyrrolo[2,3-b]pyridine-3-one derivatives as novel fibroblast growth factor receptor 4 inhibitors for the treatment of hepatocellular carcinoma.

Nanjing University of Chinese Medicine

Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPKα2β1γ1 activators.

Nanjing University of Chinese Medicine

Design, synthesis and evaluation of 2-amino-imidazol-4-one derivatives as potent β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) inhibitors.

Nanjing University of Chinese Medicine

Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471.

Nanjing University of Chinese Medicine

Design and synthesis of alkyl substituted pyridino[2,3-D]pyrimidine compounds as PI3Kα/mTOR dual inhibitors with improved pharmacokinetic properties and potent in vivo antitumor activity.

Nanjing University of Chinese Medicine

Design, synthesis and evaluate of novel dual FGFR1 and HDAC inhibitors bearing an indazole scaffold.

Nanjing University of Chinese Medicine