Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50017421
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50601782(CHEMBL5198547)
Affinity DataIC50: 0.00950nMAssay Description:Inhibition of HDAC6 (unknown origin) by microtiter plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM139295(US8614223, 73 | US10858323, Compound 1)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate pre-incubated with compound for 10 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM139323(US8614223, 101)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of N terminal GST-tagged HDAC6 (unknown origin) expressed in a baculoviral system using FTS as substrate pre-incubated with compound for 1...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50161470(6-(2-mercaptoacetylamino)-hexanoic acid quinolin-8...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50597848(CHEMBL5205841)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDE9 in human SH-SY5Y cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50597848(CHEMBL5205841)
Affinity DataIC50: 107nMAssay Description:Inhibition of HDAC6 in human SH-SY5Y cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50601783(CHEMBL5184678)
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC6 in human HeLa cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 412nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50601783(CHEMBL5184678)
Affinity DataKi:  590nMAssay Description:Binding affinity to NMDAR (unknown origin) assessed as inhibition constant by [3H]MK-801 binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed