Compile Data Set for Download or QSAR
Report error Found 3277 for UniProtKB: P49768
LigandPNGBDBM28920((2S,3S)-N-(4-chlorophenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  5.45E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28921((2S,3S)-N-(4-bromophenyl)-1-hydroxy-3-methylpentan...)
Affinity DataEC50:  2.21E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28922((2S)-N-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-h...)
Affinity DataEC50:  15nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28923(BMCL184232 Compound 8e | (2S)-N-(4-chlorophenyl)-3...)
Affinity DataEC50:  294nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28924((2S,3S)-N-(5-chlorothiophen-2-yl)-1-hydroxy-3-meth...)
Affinity DataEC50:  297nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28925((2S)-N-(5-chlorothiophen-2-yl)-3-ethyl-1-hydroxype...)
Affinity DataEC50:  25nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28926((2S)-N-(5-chlorothiophen-2-yl)-5,5,5-trifluoro-1-h...)
Affinity DataEC50:  16nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28927((2R)-N-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-h...)
Affinity DataEC50:  1.07E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28920((2S,3S)-N-(4-chlorophenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  5.45E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28928((2S,3S)-N-(3-chlorophenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  1.83E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28929((2S,3S)-N-(2-chlorophenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  5.66E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28930((2S,3S)-N-(4-fluorophenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  4.24E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28921((2S,3S)-N-(4-bromophenyl)-1-hydroxy-3-methylpentan...)
Affinity DataEC50:  2.21E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28931((2S,3S)-N-(4-cyanophenyl)-1-hydroxy-3-methylpentan...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28932((2S,3S)-1-hydroxy-3-methyl-N-(4-methylphenyl)penta...)
Affinity DataEC50:  1.43E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28933((2S,3S)-1-hydroxy-3-methyl-N-[4-(trifluoromethyl)p...)
Affinity DataEC50:  1.31E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28934((2S,3S)-N-(4-acetylphenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  6.02E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28935((2S,3S)-1-hydroxy-N-(4-methanesulfonylphenyl)-3-me...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28936((2S,3S)-1-hydroxy-3-methyl-N-(4-nitrophenyl)pentan...)
Affinity DataEC50:  2.09E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28937((2S,3S)-N-[4-(1,1-difluoroethoxy)phenyl]-1-hydroxy...)
Affinity DataEC50:  2.35E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28938((2S,3S)-N-(3,4-dichlorophenyl)-1-hydroxy-3-methylp...)
Affinity DataEC50:  3.70E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28939((2S,3S)-N-(4-chloro-3-fluorophenyl)-1-hydroxy-3-me...)
Affinity DataEC50:  7.84E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28940((2S,3S)-N-(2,3-dichlorophenyl)-1-hydroxy-3-methylp...)
Affinity DataEC50:  4.27E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28941((2S,3S)-N-(3,5-dichlorophenyl)-1-hydroxy-3-methylp...)
Affinity DataEC50:  2.35E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28942((2S,3S)-N-(2,5-dichlorophenyl)-1-hydroxy-3-methylp...)
Affinity DataEC50:  5.48E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28943((2S,3S)-1-hydroxy-3-methyl-N-phenylpentane-2-sulfo...)
Affinity DataEC50:  4.15E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28944((2S)-2-hydroxy-3-methyl-N-[(1S)-1-{[(1S)-3-methyl-...)
Affinity DataEC50:  28nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28945([(4-chlorophenyl)sulfamoyl][(2S,3S)-1-hydroxy-3-me...)
Affinity DataEC50: >3.00E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28946(4-chloro-N-[(2S,3S)-1-hydroxy-3-methylpentan-2-yl]...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28947((2S,3S)-2-{[(4-chlorophenyl)methyl]amino}-3-methyl...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28948(2-(4-chlorophenyl)-N-[(2S,3S)-1-hydroxy-3-methylpe...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28949(1-(4-chlorophenyl)-3-[(2S,3S)-1-hydroxy-3-methylpe...)
Affinity DataEC50:  4.73E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28950((2S)-N-(4-chlorophenyl)-1-hydroxypropane-2-sulfona...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28951((2S)-N-(4-chlorophenyl)-1-hydroxybutane-2-sulfonam...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28952((2S)-N-(4-chlorophenyl)-1-hydroxy-3-methylbutane-2...)
Affinity DataEC50:  4.58E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28953((2S)-N-(4-chlorophenyl)-1-hydroxy-3,3-dimethylbuta...)
Affinity DataEC50:  2.91E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28923(BMCL184232 Compound 8e | (2S)-N-(4-chlorophenyl)-3...)
Affinity DataEC50:  294nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28954((2S)-N-(4-chlorophenyl)-1-hydroxy-4-methylpentane-...)
Affinity DataEC50:  1.53E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28955((2S,3R)-N-(4-chlorophenyl)-1-hydroxy-3-methylpenta...)
Affinity DataEC50:  758nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28956((1S)-N-(4-chlorophenyl)-1-cyclohexyl-2-hydroxyetha...)
Affinity DataEC50:  1.12E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28957((1S)-N-(4-chlorophenyl)-2-hydroxy-1-phenylethane-1...)
Affinity DataEC50:  6.88E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28958((3S,4S)-N-(4-chlorophenyl)-2-hydroxy-4-methylhexan...)
Affinity DataEC50:  4.93E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28959((3S,4S)-N-(4-chlorophenyl)-2-hydroxy-2,4-dimethylh...)
Affinity DataEC50: >1.00E+5nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28960(BMCL18464 Compound 14 | (2R)-2-{[5-chloro-2-(hydro...)
Affinity DataEC50:  85nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28961(ethyl 4-[(4-chlorobenzene)sulfonyl]-4-phenylpiperi...)
Affinity DataEC50:  1.22E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28962({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorophen...)
Affinity DataEC50:  4.70nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28963(2-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  21.2nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28964({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorophen...)
Affinity DataEC50:  148nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28965(2-{1-[(4-chlorobenzene)sulfonyl]-4-(iodomethyl)cyc...)
Affinity DataEC50:  14.3nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28966({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorophen...)
Affinity DataEC50:  0.510nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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