Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 11955
TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM290431(RDEA3170 | US10100016, Verinurad (RDEA3170) | CAS ...)
Affinity DataIC50: 54.5nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 80.4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 585nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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PDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 1.09E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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PDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.16E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664708(US20240116873, Compound C)
Affinity DataIC50: 1.18E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664707(US20240116873, Compound B)
Affinity DataIC50: 2.79E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664704(US20240116873, Compound A)
Affinity DataIC50: 3.15E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664711(US20240116873, Compound E)
Affinity DataIC50: 3.42E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 6(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 6.51E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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PDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.27E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 11(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 2.74E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 8(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 4.04E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 11(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 8.38E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 8(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.00E+5nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
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