Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50008127
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 7nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 17nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 18nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 35nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 92nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 144nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 1.04E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of irinotecan-induced cytotoxicity by measuring irinotecan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 1.62E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of irinotecan-induced cytotoxicity by measuring irinotecan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 3.73E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of irinotecan-induced cytotoxicity by measuring irinotecan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed