Assay Method Information | |
| ChEMBL_1862986 (CHEMBL4363842) |
Description: | Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of irinotecan-induced cytotoxicity by measuring irinotecan IC50 at 5 uM after 72 hrs by MTT assay (Rvb = 49.2 +/- 0.46 nM) |
Affinity data for this assay | |
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