Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 8365
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243059(PTP inhibitor, 4k)
Affinity DataIC50: 2.37E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243055(PTP inhibitor, 4g)
Affinity DataIC50: 2.40E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243051(PTP inhibitor, 4c)
Affinity DataIC50: 2.66E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM23197((1S,2R,4aS,6aS,6bR,10S,12aR,12bR,14bS)-10-hydroxy-...)
Affinity DataIC50: 3.20E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243058(PTP inhibitor, 4j)
Affinity DataIC50: 3.48E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243054(PTP inhibitor, 4f)
Affinity DataIC50: 3.60E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243053(PTP inhibitor, 4e)
Affinity DataIC50: 4.18E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243056(PTP inhibitor, 4h)
Affinity DataIC50: 4.90E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243057(PTP inhibitor, 4i)
Affinity DataIC50: 7.33E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243050(PTP inhibitor, 4b)
Affinity DataIC50: 7.98E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243059(PTP inhibitor, 4k)
Affinity DataIC50: 8.54E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243059(PTP inhibitor, 4k)
Affinity DataIC50: 8.82E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243049(PTP inhibitor, 4a)
Affinity DataIC50: 9.06E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243052(PTP inhibitor, 4d)
Affinity DataIC50: 1.02E+4nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243062(PTP inhibitor, 4n)
Affinity DataIC50: 1.31E+4nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243061(PTP inhibitor, 4m)
Affinity DataIC50: 1.41E+4nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243060(PTP inhibitor, 4l)
Affinity DataIC50: 3.67E+4nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed