Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 3098
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27957((9S,10S)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataEC50:  6.90E+3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27960(CHEMBL198059 | (2R,3S)-1-[(7-methyl-2,3-dihydro-1H...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/mole IC50: 3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27959(El 737 | 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/mole IC50: 330nM EC50:  9.10nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27955((9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataKi:  320nM ΔG°:  -36.7kJ/mole IC50: 620nM EC50:  8.70nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM25769(Levalbuterol | Salbutamol,(+/-) | albuterol | Prov...)
Affinity DataKi:  510nM ΔG°:  -35.6kJ/mole IC50: 980nM EC50:  19nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27958(Planipart | 1-(4-amino-3,5-dichlorophenyl)-2-(tert...)
Affinity DataKi:  570nM ΔG°:  -35.3kJ/mole IC50: 1.30E+3nM EC50:  6.20nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27956(9-hydroxy-10-(propan-2-ylamino)-1,3-diazatricyclo[...)
Affinity DataKi:  580nM ΔG°:  -35.2kJ/mole IC50: 1.10E+3nM EC50:  13nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Intervet Innovation

LigandPNGBDBM27957((9S,10S)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataKi:  7.00E+3nM ΔG°:  -29.1kJ/mole IC50: 1.70E+4nM EC50:  1.40E+5nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Intervet Innovation

LigandPNGBDBM27955((9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataKi:  1.30E+5nM ΔG°:  -22.0kJ/mole IC50: 3.20E+5nM EC50: >1.00E+6nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed