Compile Data Set for Download or QSAR
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TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665297(US20240116909, Example 1 | 4-(5-(3-((2-(3-carboxyp...)
Affinity DataIC50: 0.0600nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604466(CHEMBL5201766)
Affinity DataIC50: 0.0623nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665300(US20240116909, Example 4 | 4-(5-(3-((2-(3-carboxyp...)
Affinity DataIC50: 0.180nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665312(US20240116909, Example 17 | (S)-4-(5-(3-((2-((S)-3...)
Affinity DataIC50: 0.190nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665315(US20240116909, Example 20 | 4-(5-(3-((2-(3-carboxy...)
Affinity DataIC50: 0.190nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604556(CHEMBL5175703)
Affinity DataIC50: 0.200nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665306(US20240116909, Example 10 | 4-(5-(3-((2-(3-carboxy...)
Affinity DataIC50: 0.280nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509399(CHEMBL4468010)
Affinity DataIC50: 0.300nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665301(US20240116909, Example 5 | Sodium (S)-4-(5-(3-((2-...)
Affinity DataIC50: 0.320nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665302(US20240116909, Example 6 | Sodium (S)-4-(5-(3-((2-...)
Affinity DataIC50: 0.360nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665304(US20240116909, Example 8 | Sodium 4-(5-(3-((2-(3-c...)
Affinity DataIC50: 0.650nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509421(CHEMBL4577528)
Affinity DataIC50: 0.700nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50547937(CHEMBL4757897)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50547938(CHEMBL4787511)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50547939(CHEMBL4755510)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50547940(CHEMBL4800391)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50547941(CHEMBL4755632)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50547942(CHEMBL4764478)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665303(US20240116909, Example 7 | 4-(5-(3-((2-(3-carboxyl...)
Affinity DataIC50: 1.04nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataIC50: 1.10nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509408(CHEMBL4459563)
Affinity DataIC50: 1.30nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509422(CHEMBL4476079)
Affinity DataIC50: 1.40nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM573856(US11453697, Example 20)
Affinity DataIC50: 1.40nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509431(CHEMBL4589856)
Affinity DataIC50: 1.5nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604561(CHEMBL5197904)
Affinity DataIC50: 1.70nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataIC50: 1.80nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604563(CHEMBL5201164)
Affinity DataIC50: 1.90nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50511088(CHEMBL4457089)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type STING (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604560(CHEMBL5180005)
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665305(US20240116909, Example 9 | 4-(5-(3-((6-bromo-2-(3-...)
Affinity DataIC50: 2.23nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665307(US20240116909, Example 11 | 4-(5-(3-((6-(3-carboxy...)
Affinity DataIC50: 2.54nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604555(CHEMBL5181746)
Affinity DataIC50: 2.90nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604562(CHEMBL5185127)
Affinity DataIC50: 3.10nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509412(CHEMBL4474321 | US11453697, Example 1)
Affinity DataIC50: 3.5nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604559(CHEMBL5174023)
Affinity DataIC50: 3.70nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataIC50: 3.90nMAssay Description:Displacement of fluorescein-labelled probe from human cytoplasmic domain of STING G230A/R293Q double mutant (155 to 341 residues) by time-resolved FR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50604557(CHEMBL5191008)
Affinity DataIC50: 4.20nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665313(US20240116909, Example 18 | 4-(5-(3-((2-((2-carbox...)
Affinity DataIC50: 4.59nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50587689(CHEMBL5197229)
Affinity DataIC50: 4.60nMAssay Description:Agonist activity at human STING incubated for 3 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of anti 6His antibody-labeled terbium cryptate binding to human wild-type full-length 6His-tagged d2-labeled STING measured after 4 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataIC50: 6.20nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataIC50: 7.10nMAssay Description:Displacement of fluorescein-labelled probe from wild type human His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataIC50: 7.20nMAssay Description:Displacement of fluorescein-labelled probe from human cytoplasmic domain of STING G230A/R293Q double mutant (155 to 341 residues) by time-resolved FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM50509430(CHEMBL4570468)
Affinity DataIC50: 8.30nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM665299(US20240116909, Example 3 | 4-(5-(3-((2-(3-carboxyp...)
Affinity DataIC50: 8.40nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM581011(US11492367, Compound 7)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM581020(US11492367, Compound 18)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM581023(US11492367, Compound 26)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM581026(US11492367, Compound 29)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetStimulator of interferon genes protein(Human)
Jacobio Pharmaceuticals Co., Ltd.

US Patent
LigandPNGBDBM581028(US11492367, Compound 31)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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