Compile Data Set for Download or QSAR
Report error Found 140 of ic50 data for polymerid = 50004212,50004579
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587908(CHEMBL5193790)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587909(CHEMBL5174073)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50140321((S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant COX-2 using [1-14C] arachidonic acid as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50229774(N-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzen...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 43nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50326830(2-(4-azido)phenyl)-8-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50: 57nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50326828(8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50326829(6-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50326831(2-(4-azido)phenyl)-6-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50: 77nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50326826(2-(4-acetamido)phenyl)-8-benzoyl-quinoline-4-carbo...)
Affinity DataIC50: 80nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50326827(2-(4-acetamido)phenyl)-6-benzoyl-quinoline-4-carbo...)
Affinity DataIC50: 85nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679785(US12011433, Compound MPA450)
Affinity DataIC50: 90nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50300870(2-(4-(methylsulfonyl)phenyl)-quinoline-4-carboxyli...)
Affinity DataIC50: 91nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679775(US12011433, Compound MPA236)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587914(CHEMBL5200917)
Affinity DataIC50: 110nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679777(US12011433, Compound MPA361)
Affinity DataIC50: 120nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587915(CHEMBL5196989)
Affinity DataIC50: 170nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598758(CHEMBL5199117)
Affinity DataIC50: 190nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598765(CHEMBL5207189)
Affinity DataIC50: 240nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679767(US12011433, Compound GAMOF11)
Affinity DataIC50: 270nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 293nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50140321((S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 300nMAssay Description:Inhibition of COX-2 in LPS-stimulated human whole blood assessed as reduction in PGE2 production by immunoassayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515743(CHEMBL4448990)
Affinity DataIC50: 367nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50140321((S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598750(CHEMBL5193981)
Affinity DataIC50: 490nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515744(CHEMBL4441570)
Affinity DataIC50: 513nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598754(CHEMBL5173923)
Affinity DataIC50: 550nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598757(CHEMBL5191029)
Affinity DataIC50: 560nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679765(US12011433, Compound GlaMOF0)
Affinity DataIC50: 700nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679786(US12011433, Compound MPA362)
Affinity DataIC50: 800nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515745(CHEMBL4474644)
Affinity DataIC50: 915nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598766(CHEMBL5170447)
Affinity DataIC50: 930nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50558934(CHEMBL4754218)
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM35905(cid_610479 | flufenamic acid analogue, 32 | Tolfen...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587916(CHEMBL5198027)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50589148(CHEMBL5187847)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM35905(cid_610479 | flufenamic acid analogue, 32 | Tolfen...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50592551(CHEMBL5206236)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM679770(US12011433, Compound MPA190)
Affinity DataIC50: 2.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598747(CHEMBL5207774)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50558936(CHEMBL4794507)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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