Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Glutathione peroxidase 1'
TargetGlutathione peroxidase 1(Human)
Ernst-Moritz-Arndt University Greifswald

Curated by ChEMBL
LigandPNGBDBM50395834(CHEMBL2165394)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of GPx1 using gultathione as substrate by glutathione reductase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione peroxidase 1(Human)
Ernst-Moritz-Arndt University Greifswald

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataKi:  3.27E+4nM IC50: 4.43E+4nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione peroxidase 1(Human)
Ernst-Moritz-Arndt University Greifswald

Curated by ChEMBL
LigandPNGBDBM50049707((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)
Affinity DataKi:  3.41E+4nM IC50: 4.86E+4nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione peroxidase 1(Human)
Ernst-Moritz-Arndt University Greifswald

Curated by ChEMBL
LigandPNGBDBM237182(Ceftizoxime)
Affinity DataKi:  1.21E+5nM IC50: 1.86E+5nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione peroxidase 1(Human)
Ernst-Moritz-Arndt University Greifswald

Curated by ChEMBL
LigandPNGBDBM50390999(CEFOPERAZONE)
Affinity DataKi:  2.45E+5nM IC50: 3.13E+5nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed