Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with Target = 'Glucokinase 1, putative'
TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514034(US11059842, Compound 28 | 6,8-Dibromo-2-(4-ethoxy-...)
Affinity DataIC50: 356nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514033(US11059842, Compound 27 | 6,8-Dibromo-2-(3,4-dimet...)
Affinity DataIC50: 416nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514032(US11059842, Compound 26 | 6-Bromo-2-(3,4-dimethoxy...)
Affinity DataIC50: 435nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514031(US11059842, Compound 25 | -Bromo-2-(3,4-dimethoxyp...)
Affinity DataIC50: 515nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514029(US11059842, Compound 23 | 6-Bromo-2-(4-ethoxy-3-me...)
Affinity DataIC50: 614nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514036(US11059842, Compound 30 | 6,8-Dichloro-2-(3,4-diet...)
Affinity DataIC50: 664nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514029(US11059842, Compound 23 | 6-Bromo-2-(4-ethoxy-3-me...)
Affinity DataIC50: 743nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514026(US11059842, Compound 20)
Affinity DataIC50: 862nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514024(US11059842, Compound 19)
Affinity DataIC50: 902nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514037(US11059842, Compound 31)
Affinity DataIC50: 1.12E+3nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514030(US11059842, Compound 24 | 6-Bromo-2-(3,4-diethoxyp...)
Affinity DataIC50: 1.19E+3nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514028(US11059842, Compound 22)
Affinity DataIC50: 1.28E+3nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514027(US11059842, Compound 21)
Affinity DataIC50: 1.67E+3nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514001(US11059842, Compound 1)
Affinity DataIC50: 1.61E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514001(US11059842, Compound 1)
Affinity DataIC50: 1.61E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514019(US11059842, Compound 14)
Affinity DataIC50: 1.99E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514019(US11059842, Compound 14)
Affinity DataIC50: 1.99E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514021(US11059842, Compound 16)
Affinity DataIC50: 2.03E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514021(US11059842, Compound 16)
Affinity DataIC50: 2.03E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514005(US11059842, Compound 5)
Affinity DataIC50: 2.72E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514005(US11059842, Compound 5)
Affinity DataIC50: 2.72E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514023(US11059842, Compound 18)
Affinity DataIC50: 3.64E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514020(US11059842, Compound 15)
Affinity DataIC50: 3.79E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514013(US11059842, Compound 9)
Affinity DataIC50: 3.84E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514011(US11059842, Compound 8)
Affinity DataIC50: 3.84E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514015(US11059842, Compound 11)
Affinity DataIC50: 4.25E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514010(US11059842, Compound 7)
Affinity DataIC50: 4.35E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514006(US11059842, Compound 6)
Affinity DataIC50: 4.99E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514003(US11059842, Compound 3)
Affinity DataIC50: 5.29E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514017(US11059842, Compound 13)
Affinity DataIC50: 5.53E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514002(US11059842, Compound 2)
Affinity DataIC50: 6.62E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514022(US11059842, Compound 17)
Affinity DataIC50: 6.66E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514016(US11059842, Compound 12)
Affinity DataIC50: 6.75E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514014(US11059842, Compound 10)
Affinity DataIC50: 8.00E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514004(US11059842, Compound 4)
Affinity DataIC50: 8.00E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514001(US11059842, Compound 1)
Affinity DataKi:  3.20E+4nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlucokinase 1, putative(Trypanosoma cruzi (strain CL Brener))
University of South Carolina

US Patent
LigandPNGBDBM514005(US11059842, Compound 5)
Affinity DataKi:  1.39E+5nMAssay Description:The 16 compounds showing substantial inhibition against TcGlcK at compound concentrations of 20 μM were then examined in a confirmatory assay in...More data for this Ligand-Target Pair
In DepthDetails
US Patent