Compile Data Set for Download or QSAR
Report error Found 455 Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [501-599]'
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM724((3S)-oxolan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-...)
Affinity DataIC50: 0.0300nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM723(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(2...)
Affinity DataIC50: 0.300nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM517(Crixivan | CHEMBL115 | L-735, 524 | MK639 | Indina...)
Affinity DataIC50: 0.360nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10149(lysine sulfonamide analogue 13SS | methyl N-[(1S)-...)
Affinity DataIC50: 0.5nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10148(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 0.521nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM751(Hydroxyethylene dipeptide isostere | CHEMBL289195 ...)
Affinity DataIC50: 0.600nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10146(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 1.20nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10147(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 1.20nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM721(Pyrrolinone deriv. 2 | (3S)-oxolan-3-yl N-[(2S,3S)...)
Affinity DataIC50: 1.30nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10154((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataIC50: 1.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM726((3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2...)
Affinity DataIC50: 2nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM727((3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2...)
Affinity DataIC50: 2nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10156((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataIC50: 3.80nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM728((3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-3-oxo...)
Affinity DataIC50: 5.70nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10145(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 6.5nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM720(Pyrrolinone deriv. 1 | tert-butyl N-[(2S,3S)-4-[(2...)
Affinity DataIC50: 10nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM725(Pyrrolinone deriv. 6 | tert-butyl N-[(2S,3S)-4-[(2...)
Affinity DataIC50: 11.9nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10141(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 12nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10149(lysine sulfonamide analogue 13SS | methyl N-[(1S)-...)
Affinity DataIC50: 13nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
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PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10150(lysine sulfonamide analogue 13RR | methyl N-[(1R)-...)
Affinity DataIC50: 25nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10143(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 40nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10144(lysine sulfonamide analogue 8)
Affinity DataIC50: 130nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9606((2R,3S,4S,5R)-1,6-bis[(2-fluorophenyl)methoxy]-2,5...)
Affinity DataIC50: 200nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10142(methyl N-[(S)-{[(5R)-5-[(4-aminobenzene)(2-methylp...)
Affinity DataIC50: 300nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM10150(lysine sulfonamide analogue 13RR | methyl N-[(1R)-...)
Affinity DataIC50: 300nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9594((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(2,6-difl...)
Affinity DataIC50: 330nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9605((2R,3S,4S,5R)-1,6-bis[(2,6-difluorophenyl)methoxy]...)
Affinity DataIC50: 330nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9593((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(2-fluoro...)
Affinity DataIC50: 600nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9576((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-fluoro...)
Affinity DataIC50: 700nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9604((2R,3S,4S,5R)-1,6-bis[(2-fluorophenyl)methoxy]-2,5...)
Affinity DataIC50: 800nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9603((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis({[4-(hydr...)
Affinity DataIC50: 1.20E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9592((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(3-fluoro...)
Affinity DataIC50: 1.50E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9574((2R,3S,4S,5R)-1,2,5,6-tetrakis[(4-fluorophenyl)met...)
Affinity DataIC50: 1.60E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9579((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(3-fluoro...)
Affinity DataIC50: 1.80E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9577((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-chloro...)
Affinity DataIC50: 2.00E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9601(tetra-O-benzyl-d-mannitol deriv. 1ee)
Affinity DataIC50: 2.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9578((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-bromop...)
Affinity DataIC50: 2.10E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9571((2R,3S,4S,5R)-1,2,5,6-tetrakis(benzyloxy)hexane-3,...)
Affinity DataIC50: 2.40E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9591((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-fluoro...)
Affinity DataIC50: 2.50E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9582((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(2,4-difl...)
Affinity DataIC50: 2.60E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9599((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-methyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9575(4-({[(2R,3S,4S,5R)-1,5,6-tris[(4-cyanophenyl)metho...)
Affinity DataIC50: 3.10E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9580((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(2-fluoro...)
Affinity DataIC50: 3.70E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9584((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-methyl...)
Affinity DataIC50: 3.70E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9595((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(2,4-difl...)
Affinity DataIC50: 4.20E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9600(4-({[(2R,3S,4S,5R)-2,5-bis(benzyloxy)-6-[(4-cyanop...)
Affinity DataIC50: 4.30E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9598((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis({[4-(trif...)
Affinity DataIC50: 5.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9602(4-({[(2R,3S,4S,5R)-2,5-bis(benzyloxy)-6-[(4-carbox...)
Affinity DataIC50: 5.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9597((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-chloro...)
Affinity DataIC50: 5.20E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM9585(4-({[(2R,3S,4S,5R)-1,6-bis(benzyloxy)-5-[(4-cyanop...)
Affinity DataIC50: 5.40E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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