Compile Data Set for Download or QSAR
Report error Found 172 Enz. Inhib. hit(s) with Target = 'Cytochrome c oxidase subunit 1'
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679764(US12011433, Compound mofezolac)
Affinity DataIC50: 7.90nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679777(US12011433, Compound MPA361)
Affinity DataIC50: 13nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679784(US12011433, Compound MPA439)
Affinity DataIC50: 49nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679768(US12011433, Compound MPA195)
Affinity DataIC50: 70nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679782(US12011433, Compound MPA462)
Affinity DataIC50: 80nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679765(US12011433, Compound GlaMOF0)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679767(US12011433, Compound GAMOF11)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679770(US12011433, Compound MPA190)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50343721(3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphen...)
Affinity DataIC50: 130nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679781(US12011433, Compound MPA415)
Affinity DataIC50: 150nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50343722(3-(4-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-(2...)
Affinity DataIC50: 240nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50140321((S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 280nMAssay Description:Inhibition of COX-1 in human whole blood assessed as reduction in thromboxane B2 production by immunoassayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50140321((S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant COX-1 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679772(US12011433, Compound MPA230)
Affinity DataIC50: 700nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50556692(CHEMBL4789452 | US12011433, MPA 290)
Affinity DataIC50: 950nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679773(US12011433, Compound 270)
Affinity DataIC50: 1.10E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50140321((S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of human recombinant COX-1 using [1-14C] arachidonic acid as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668573(US11964949, Compound OTB-261)
Affinity DataIC50: 2.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668521(US11964949, Compound OTB-407)
Affinity DataIC50: 3.08E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679769(US12011433, Compound MPA199)
Affinity DataIC50: 3.30E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668523(US11964949, Compound OTB-408)
Affinity DataIC50: 3.61E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668574(US11964949, Compound OTB-523)
Affinity DataIC50: 4.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668559(US11964949, Compound OTB-510)
Affinity DataIC50: 5.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668566(US11964949, Compound OTB-509)
Affinity DataIC50: 5.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668620(US11964949, Compound OBD-048)
Affinity DataIC50: 5.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679780(US12011433, Compound MPA354)
Affinity DataIC50: 5.50E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50513906(CHEMBL4549769)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668592(US11964949, Compound OTB-244)
Affinity DataIC50: 6.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668611(US11964949, Compound OBD-051)
Affinity DataIC50: 6.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668621(US11964949, Compound OBD-049)
Affinity DataIC50: 6.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679776(US12011433, Compound MPA15(DQ3))
Affinity DataIC50: 6.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668579(US11964949, Compound OTB-249)
Affinity DataIC50: 7.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668616(US11964949, Compound OBD-110)
Affinity DataIC50: 7.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668617(US11964949, Compound OBD-111)
Affinity DataIC50: 7.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679779(US12011433, Compound MPA434)
Affinity DataIC50: 7.10E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668538(US11964949, Compound OTB-120)
Affinity DataIC50: 7.27E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668531(US11964949, Compound OBD-006)
Affinity DataIC50: 7.49E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668528(US11964949, Compound OTB-137)
Affinity DataIC50: 7.64E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668557(US11964949, Compound OTB-506)
Affinity DataIC50: 8.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668565(US11964949, Compound OTB-508)
Affinity DataIC50: 8.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668524(US11964949, Compound OTB-409)
Affinity DataIC50: 8.51E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668525(US11964949, Compound OTB-411)
Affinity DataIC50: 8.73E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668563(US11964949, Compound OTB-511)
Affinity DataIC50: 9.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679778(US12011433, Compound MPA448)
Affinity DataIC50: 9.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668520(US11964949, Compound OTB-413)
Affinity DataIC50: 9.13E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326826(2-(4-acetamido)phenyl)-8-benzoyl-quinoline-4-carbo...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668519(US11964949, Compound OTB-412)
Affinity DataIC50: 1.00E+4nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668558(US11964949, Compound OTB-507)
Affinity DataIC50: 1.00E+4nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM668578(US11964949, Compound OTB-247)
Affinity DataIC50: 1.00E+4nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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