BDBM92455 CHEMBL265470::STO-609

SMILES OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c3cccc1c23

InChI Key InChIKey=MYKOWOGZBMOVBJ-UHFFFAOYSA-N

Data  15 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 92455   

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCalcium/calmodulin-dependent protein kinase kinase 2 [ P274E](Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 2.42E+4nMpH: 7.5 T: 2°CAssay Description:The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMyosin light chain kinase, smooth muscle(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 3.18E+4nMAssay Description:Binding affinity at MLCKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 381nMAssay Description:Inhibition of CaM-KKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 127nMAssay Description:Inhibition of CaM-KKbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of CaM-K4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 10nMAssay Description:Inhibition of CAMKKbeta in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 110nMAssay Description:Inhibition of PIM2 in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 120nMAssay Description:Inhibition of MNK1 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 950nMAssay Description:Inhibition of DYRK2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 120nMAssay Description:Inhibition of CAMKKalpha in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 83nMAssay Description:Inhibition of PIM3 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 120nMAssay Description:Inhibition of CaMKK2 (161 to 449 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) star cells incubated for 20 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50: 120nMAssay Description:Inhibition of CaMKK1 (unknown origin) incubated for 20 mins in presence of kinase tracer 236 by TR-FRETMore data for this Ligand-Target Pair
In DepthDetails
PubMed