BDBM201 (2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-acetamido-3-methylbutanehydrazido]-3-hydroxy-1-phenylbutan-2-yl]-2-acetamido-3-methylbutanamide::CGP 53820

SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(CC1CCCCC1)NC(=O)[C@@H](NC(C)=O)C(C)C

InChI Key InChIKey=JNBVLGDICHLLTN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 201   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 8.5nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
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PubMed
TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 7.50E+3nMAssay Description:The compound was tested for its inhibitory activity against human cathepsin DMore data for this Ligand-Target Pair
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TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 5.80E+4nMAssay Description:The compound was tested for its inhibitory activity against human reninMore data for this Ligand-Target Pair
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TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was tested for its inhibitory activity against human pepsinMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGastricsin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was tested for its inhibitory activity against human gastricsinMore data for this Ligand-Target Pair
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TargetCathepsin E(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 2.00E+3nMAssay Description:The compound was tested for its inhibitory activity against human cathepsin EMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 9nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In DepthDetails Article