BDBM21342 (4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide::CHEMBL263881::LSD::LSD 25::LSD,(+)::LSD,l-::Lysergic Acid Diethylamide::Lysergic Acid Diethylamide Tartrate::US20240166618, Compound LSD::[3H]-LSD::d-Isolysergic acid amide
SMILES CCN(CC)C(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34
InChI Key InChIKey=VAYOSLLFUXYJDT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 94 hits for monomerid = 21342
Affinity DataEC50: 15nMAssay Description:Functional potency at the rat 5-hydroxytryptamine 2A receptor as effective concentration EC50 for stimulating Phosphoinositide accumulationMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 13nMAssay Description:Agonist activity at human 5HT2A receptor transfected in HEK293T cells assessed as beta arrestin-2 recruitment measured for 2 hrs by luminescent assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9.80nMAssay Description:Tested for its ability to activate phospholipase C by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human 5HT2A receptor transfected in HEK293T cells assessed as mini Galphaq recruitment measured for 2 hrs by luminescent assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9.80nMAssay Description:Activity at rat 5HT2A receptor assessed as 5-HT-stimulated IP3 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at human 5HT2A S159A mutant transfected in HEK293T cells assessed as beta arrestin-2 recruitment measured for 2 hrs by luminescent a...More data for this Ligand-Target Pair
Affinity DataEC50: 5.40nMAssay Description:Agonist activity at human 5HT2A S159A mutant transfected in HEK293T cells assessed as mini Galphaq recruitment measured for 2 hrs by luminescent assa...More data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Tested in vitro for its ability to bind to 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A human cloned receptors in HEK293 cells using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Compound was tested for binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates,...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor human cloned receptors in HEK 293 cells using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity to human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOIMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Compound was tested for binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor alpha using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity of [3H]- ketanserin labelled towards Rat cortical 5-hydroxytryptamine 2A receptor using radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amidesMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor human cloned receptors in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Binding affinity of [3H]- -8-OH-DPAT labelled towards Rat Hippocampal 5-hydroxytryptamine 1A receptor using radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]8-OH-DPAT by lysergic acid amidesMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Affinity in displacing [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor using [125I]DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [125I]DOI from rat 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOIMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 7 human receptorsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 6 human cloned receptors in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortex using [125]-(R)-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Binding affinities against 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair