BDBM241952 Fukugetin

SMILES Oc1ccc(cc1)C1Oc2cc(O)cc(O)c2C(=O)C1c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)c(O)c1

InChI Key InChIKey=GFWPWSNIXRDQJC-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 241952   

TargetCruzipain(Trypanosoma cruzi)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPapain(Papaya)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Papaya papain using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataKi:  1.00E+3nMAssay Description:To characterize the type and extent inhibition of papain by fukugetin, papain (0.04 nM) was incubated with four concentrations of fukugetin (1.5, 3, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetPapain(Papaya)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataKi:  1.34E+4nMAssay Description:To characterize the type and extent inhibition of papain by fukugetin, papain (0.04 nM) was incubated with four concentrations of fukugetin (1.5, 3, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed