BDBM720 Pyrrolinone deriv. 1::Pyrrolinone inhibitor 1::tert-butyl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2S)-4-[(1R)-1-carbamoyl-2-phenylethyl]-2-(2-methylpropyl)-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate

SMILES CC(C)C[C@]1(N=CC([C@@H](Cc2ccccc2)C(N)=O)C1=O)C1C=N[C@](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)(Cc2ccccc2)C1=O

InChI Key InChIKey=ZXPYRRBCVSDGNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM720(Pyrrolinone deriv. 1 | tert-butyl N-[(2S,3S)-4-[(2...)
Affinity DataIC50: 10nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed