BDBM701114 (R)-3-Methyl-4-(9-methyl-2- ((4-phenyl-1H-imidazol-2- yl)ethynyl)-9H-purin-6- yl)morpholine::US20240343729, Example 29

SMILES C[C@@H]1COCCN1c1nc(C#Cc2nc(-c3ccccc3)c[nH]2)nc2c1ncn2C

InChI Key InChIKey=LBGHJISATMTULP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701114   

TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
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US Patent

LigandBDBM701114((R)-3-Methyl-4-(9-methyl-2- ((4-phenyl-1H-imidazol...)Copy SMILESCopy InChI

Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoSimilars

In Depth
Date in BDB:
2/23/2025
Entry Details
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