BDBM701111 (3aR,6aS)-5-(1- (Cyclopropylmethyl)-6-((4- phenyl-1H-imidazol-2- yl)ethynyl)-1H-pyrazolo[3,4- d]pyrimidin-4- yl)hexahydro-1H-furo[3,4- c]pyrrole::US20240343729, Example 26

SMILES C(#Cc1nc(-c2ccccc2)c[nH]1)c1nc(N2C[C@H]3COC[C@H]3C2)c2cnn(CC3CC3)c2n1

InChI Key InChIKey=HPYUCCMNAQNREE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701111   

TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
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US Patent

LigandBDBM701111((3aR,6aS)-5-(1- (Cyclopropylmethyl)-6-((4- phenyl-...)Copy SMILESCopy InChI

Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoSimilars

In Depth
Date in BDB:
2/23/2025
Entry Details
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