BDBM701109 US20240343729, Example 24

SMILES Cn1cc(-c2ccccc2)nc1C#Cc1nc(N2CCS(=N)(=O)CC2)c2cnn(C)c2n1

InChI Key InChIKey=JSIVCGNFTHRTOS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701109   

TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
Benevolentai Cambridge

US Patent

LigandBDBM701109(US20240343729, Example 24)Copy SMILESCopy InChI

Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
2/23/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL