BDBM701106 US20240343729, Example 21

SMILES C[C@@H]1COCCN1c1nc(C#Cc2nc(-c3ccccc3)cn2C)nc2c1ncn2C

InChI Key InChIKey=WUZKRULQFWZCLN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701106   

TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
Benevolentai Cambridge

US Patent

LigandBDBM701106(US20240343729, Example 21)Copy SMILESCopy InChI

Affinity DataIC50: 0.0500nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
2/23/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL