BDBM700257 N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]methyl]quinazoline-4-carboxamide::US20240336591, Example 17

SMILES Cn1cc(c(n1)-c1ccc(OCc2nc(C(=O)N=S(C)(C)=O)c3ccccc3n2)cc1)-c1ccncc1

InChI Key InChIKey=NXFGYHQDWWWIDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700257   

LigandPNGBDBM700257(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[1-m...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

LigandPNGBDBM700257(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[1-m...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent