BDBM700249 N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1-methyl-4-(4- pyridyl)pyrazol-3- yl]phenoxy]methyl] quinoline-4- carboxamide::US20240336591, Example 11

SMILES Cn1cc(c(n1)-c1ccc(OCc2cc(C(=O)N=S(C)(C)=O)c3ccccc3n2)cc1)-c1ccncc1

InChI Key InChIKey=ROVIGCIZIBAMFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700249   

LigandPNGBDBM700249(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

LigandPNGBDBM700249(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent