BDBM695535 US12084416, Example 127

SMILES C=CCN1CCC[C@H]1\C=C\S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=TWNZOROKVJRRPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695535   

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandPNGBDBM695535(US12084416, Example 127)
Affinity DataIC50: 5.60nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent