BDBM695526 US12084416, Example 63

SMILES O=C(Nc1c2CCCc2cc2CCCc12)NS(=O)(=O)\C=C\[C@@H]1CCCN1S(=O)(=O)c1cccnc1

InChI Key InChIKey=WBGXICSZCLHLRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695526   

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandPNGBDBM695526(US12084416, Example 63)
Affinity DataIC50: 8nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent