BDBM692285 (R,E)-11-methyl-17-(1-methyl-1H-1,2,4-triazol-5-yl)-12,13-dihydro-11H-2,6-diaza-1(2,1)-benzo[d]imidazola-4(1,3)-benzenacycloundecaphane-3,5-dione::US20240279233, Example 85::US20240279233, Example 86

SMILES C[C@H]1CCCCNC(=O)c2cccc(c2)C(=O)Nc2nc3cccc(-c4ncnn4C)c3n12

InChI Key InChIKey=RNYMHBCNZCJMRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 692285   

LigandPNGBDBM692285(US20240279233, Example 85 | (R,E)-11-methyl-17-(1-...)
Affinity DataIC50: 3nMAssay Description:Assay kits from Promega Corporation V4089 were used according to manufacturer's instructions and adapted as outlined here. ADP-Glo Kinase Assay k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

LigandPNGBDBM692285(US20240279233, Example 85 | (R,E)-11-methyl-17-(1-...)
Affinity DataIC50: 4nMAssay Description:Assay kits from Promega Corporation V4089 were used according to manufacturer's instructions and adapted as outlined here. ADP-Glo Kinase Assay k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

LigandPNGBDBM692285(US20240279233, Example 85 | (R,E)-11-methyl-17-(1-...)
Affinity DataIC50: 9nMAssay Description:Assay kits from Promega Corporation V4089 were used according to manufacturer's instructions and adapted as outlined here. ADP-Glo Kinase Assay k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent