BDBM688420 2-chloro-N-[3-methyl-5-(2- phenylethynyl)-2-pyridyl]-5-(5- tetrahydrofuran-3-yl-1,2,4-oxadiazol- 3-yl)benzamide::US20240190824, Compound 19

SMILES Cc1cc(cnc1NC(=O)c1cc(ccc1Cl)-c1noc(n1)C1CCOC1)C#Cc1ccccc1

InChI Key InChIKey=KAQBZMBVWBTNNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688420   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688420(US20240190824, Compound 19 | 2-chloro-N-[3-methyl-...)
Affinity DataIC50: 50nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688420(US20240190824, Compound 19 | 2-chloro-N-[3-methyl-...)
Affinity DataIC50: 191nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated on glass coverslips, and voltage clamped in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent