BDBM687757 Synthesis of N-(1-(2-fluorophenyl)cyclopropyl)-1-methyl-6-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide ::US20240246972, Compound 4
SMILES Cn1c(cc2ccc(nc12)-c1cn[nH]c1)C(=O)NC1(CC1)c1ccccc1F
InChI Key InChIKey=QTMFCQXLQBJZQU-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 687757
Affinity DataIC50: 37.4nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Human)
Avicenna Biosciences, Inc.
US Patent
Avicenna Biosciences, Inc.
US Patent
Affinity DataIC50: 6.60nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Avicenna Biosciences, Inc.
US Patent
Avicenna Biosciences, Inc.
US Patent
Affinity DataIC50: 9.90nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Affinity DataIC50: 37.4nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Human)
Avicenna Biosciences, Inc.
US Patent
Avicenna Biosciences, Inc.
US Patent
Affinity DataIC50: 6.60nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Avicenna Biosciences, Inc.
US Patent
Avicenna Biosciences, Inc.
US Patent
Affinity DataIC50: 9.90nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair