BDBM664709 US20240116873, Compound D

SMILES CC(C)(Sc1ccnc2ccc(cc12)C(F)(F)F)C(=O)NS(C)(=O)=O

InChI Key InChIKey=CCNMFGQOJWLCFA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 664709   

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 80.4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
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TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.16E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSolute carrier family 22 member 6(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.27E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSolute carrier family 22 member 8(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.00E+5nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSolute carrier family 22 member 11(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM664709(US20240116873, Compound D)
Affinity DataIC50: 8.38E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent