BDBM576112 N-(3-(3,5-difluorobenzyl)-5- (6-methyl-7-oxo-6,7-dihydro- 1H-pyrrolo[2,3-c]pyridin-4-yl)- 3H-imidazo[4,5-b]pyridin-7- yl)ethanesulfonamide::US11466034, Example 62

SMILES CCS(=O)(=O)Nc1cc(nc2n(Cc3cc(F)cc(F)c3)cnc12)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=JXMXQJCEXZEYBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576112   

TargetBromodomain-containing protein 4 [44-167](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576112(N-(3-(3,5-difluorobenzyl)-5- (6-methyl-7-oxo-6,7-d...)
Affinity DataIC50: 1.30nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576112(N-(3-(3,5-difluorobenzyl)-5- (6-methyl-7-oxo-6,7-d...)
Affinity DataIC50: 1.20nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent