BDBM576086 Compound 39 (4-(1-(4-chlorobenzyl)-1H-pyrazolo[4,3-b]pyridin-6-yl)-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)::US11466034, Example 39

SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc2c(cn(C)c(=O)c12)-c1cnc2cnn(Cc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=HFLTVRVJZPUMBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576086   

TargetBromodomain-containing protein 4 [44-167](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576086(Compound 39 (4-(1-(4-chlorobenzyl)-1H-pyrazolo[4,3...)
Affinity DataIC50: 21.2nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576086(Compound 39 (4-(1-(4-chlorobenzyl)-1H-pyrazolo[4,3...)
Affinity DataIC50: 7.90nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent